Wherland Sandbox 3

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<scene name='70/707393/3fpx_domains_cu/3'>domains</scene> colored green, blue, and yellow. The copper ions are represented by maroon spheres. Adding the
<scene name='70/707393/3fpx_domains_cu/3'>domains</scene> colored green, blue, and yellow. The copper ions are represented by maroon spheres. Adding the
<scene name='70/707393/3fpx_domains_cu_ligands/3'>ligands</scene> to the Cu ions shows that they come from different domains. The ligands of the T1 Cu ion (His-395 and 458 and Cys-453) all come from the yellow domain 3. The ligands of one T3 Cu ion come from the yellow domain 3 (His-400 and 452) and the blue domain 1(His 111). The ligands of the other T3 Cu ion also come from the yellow and blue domains 3 and 1, but two (His-66 and 109) come from the blue domain 1 and only one from the yellow domain 3 (His-454). The ligands of the T2 Cu ion come from the blue domain 1 (His 64) and yellow domain 3 (His-398) and in addition there are three water molecules, one in the center of the TNC, one bridging the T3 Cu ions, and one just associated with the T2 Cu ion. None of the ligands come from the blue domain 2, the middle of the sequence. The ligands can be seen better without the surrounding chains, and with the bridging
<scene name='70/707393/3fpx_domains_cu_ligands/3'>ligands</scene> to the Cu ions shows that they come from different domains. The ligands of the T1 Cu ion (His-395 and 458 and Cys-453) all come from the yellow domain 3. The ligands of one T3 Cu ion come from the yellow domain 3 (His-400 and 452) and the blue domain 1(His 111). The ligands of the other T3 Cu ion also come from the yellow and blue domains 3 and 1, but two (His-66 and 109) come from the blue domain 1 and only one from the yellow domain 3 (His-454). The ligands of the T2 Cu ion come from the blue domain 1 (His 64) and yellow domain 3 (His-398) and in addition there are three water molecules, one in the center of the TNC, one bridging the T3 Cu ions, and one just associated with the T2 Cu ion. None of the ligands come from the blue domain 2, the middle of the sequence. The ligands can be seen better without the surrounding chains, and with the bridging
-
<scene name='70/707393/3fpx_domains_cu_ligands_links/1'>residues</scene> between ligands (Trp-65, Ser-110, and Leu-399).
+
<scene name='70/707393/3fpx_domains_cu_ligands_links/2'>bridging</scene> residues between ligands (Trp-65, Ser-110, and Leu-399).
== Disease ==
== Disease ==

Revision as of 12:13, 19 July 2015

Introduction

Multicopper Oxidases

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References

Proteopedia Page Contributors and Editors (what is this?)

Scot Wherland

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