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Tumor necrosis factor receptor

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'''Tumor necrosis factor receptor''' (TNFR) or '''death receptor''' is a trimeric cytokine receptor which binds TNF. TNFR family contains several members and superfamily (TNFRSF) members. The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains.<br />
'''Tumor necrosis factor receptor''' (TNFR) or '''death receptor''' is a trimeric cytokine receptor which binds TNF. TNFR family contains several members and superfamily (TNFRSF) members. The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains.<br />
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* '''TNFRSF 1''' is called '''Lymphotoxin-α or TNF-β''';<br />
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* '''TNFRSF 4''' is called '''OX40L receptor''';<br />
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* '''TNFRSF 5''' is called '''CD40L receptor''';<br />
* '''TNFRSF 6''' is called '''Fas''';<br />
* '''TNFRSF 6''' is called '''Fas''';<br />
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* '''TNFRSF 9''' is called '''4-1BBL''';<br />
* '''TNFRSF 10B''' is called '''Dr5''';<br />
* '''TNFRSF 10B''' is called '''Dr5''';<br />
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* '''TNFRSF 11''' is called '''RANKL''';<br />
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* '''TNFRSF 11A''' is called '''RANK''';<br />
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* '''TNFRSF 12''' is called '''TWEAK''';<br />
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* '''TNFRSF 12A''' is called '''TWEAKR''';<br />
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* '''TNFRSF 13''' is called '''APRIL''';<br />
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* '''TNFRSF 13B''' is called '''BAFF or sTALL-1''';<br />
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* '''TNFRSF 13C''' is called '''BAFF receptor''';<br />
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* '''TNFRSF 14''' is called '''LIGHT''';<br />
* '''TNFRSF 16''' is called '''Nerve growth factor receptor''';<br />
* '''TNFRSF 16''' is called '''Nerve growth factor receptor''';<br />
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* '''TNFRSF 18''' is called '''GITRL''';<br />
* '''TNFRSF 21''' is called '''Dr6''';<br />
* '''TNFRSF 21''' is called '''Dr6''';<br />
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* '''TNFRSF 11A''' is called '''RANK''';<br />
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* '''TNFRSF 18''' is called '''GITRL'''.
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== Disease ==
== Disease ==

Revision as of 09:39, 21 July 2015

Structure of human TNFRSF-18 extracellular domain (PDB code 2q1m).

Drag the structure with the mouse to rotate

3D structures of tumor necrosis factor receptor

Updated on 21-July-2015

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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