5ak8
From Proteopedia
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| - | ''' | + | ==Structure of C351A mutant of Porphyromonas gingivalis peptidylarginine deiminase== |
| - | + | <StructureSection load='5ak8' size='340' side='right' caption='[[5ak8]], [[Resolution|resolution]] 1.48Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ak8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AK8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AK8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ak7|5ak7]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ak8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ak8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5ak8 RCSB], [http://www.ebi.ac.uk/pdbsum/5ak8 PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | + | == Function == | |
| + | [[http://www.uniprot.org/uniprot/PAD_PORGI PAD_PORGI]] Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth.<ref>PMID:10377098</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Burgess-Brown, N]] | [[Category: Burgess-Brown, N]] | ||
| - | [[Category: Yue, W.W]] | ||
[[Category: Kiyani, W]] | [[Category: Kiyani, W]] | ||
| - | [[Category: Shrestha, L]] | ||
| - | [[Category: Venables, P.J]] | ||
[[Category: Kopec, J]] | [[Category: Kopec, J]] | ||
[[Category: Montgomery, A]] | [[Category: Montgomery, A]] | ||
| + | [[Category: Nowak, R]] | ||
| + | [[Category: Shrestha, L]] | ||
| + | [[Category: Venables, P J]] | ||
| + | [[Category: Yue, W W]] | ||
| + | [[Category: Hydrolase]] | ||
Revision as of 14:20, 22 July 2015
Structure of C351A mutant of Porphyromonas gingivalis peptidylarginine deiminase
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