TNF receptor-associated factor
From Proteopedia
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'''TNF receptor-associated factor''' (TRAF) are signal transducers and are involved in regulation of apoptosis, inflammation and antiviral response. There are 7 known TRAF proteins. All TRAF proteins share a C-terminal homology region named TRAF domain which can bind the cytoplasmic domain of receptors and other TRAF proteins. TRAF2-6 have N-terminal RING and zinc finger motifs. TRAF2, TRAF5 and TRAF6 mediate activation of NF-κB and JNK. | '''TNF receptor-associated factor''' (TRAF) are signal transducers and are involved in regulation of apoptosis, inflammation and antiviral response. There are 7 known TRAF proteins. All TRAF proteins share a C-terminal homology region named TRAF domain which can bind the cytoplasmic domain of receptors and other TRAF proteins. TRAF2-6 have N-terminal RING and zinc finger motifs. TRAF2, TRAF5 and TRAF6 mediate activation of NF-κB and JNK. | ||
Revision as of 06:47, 23 July 2015
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3D Structures of TNF receptor-associated factor
Updated on 23-July-2015
