5c6s

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m (Protected "5c6s" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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==Human Bromodomain and PHD Finger Containing 1, PWWP domain in complex with XST005904a==
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<StructureSection load='5c6s' size='340' side='right' caption='[[5c6s]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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The entry 5c6s is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5c6s]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C6S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C6S FirstGlance]. <br>
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Authors: DONG, A., DOBROVETSKY, E., MADER, P., Santhakumar, S., TEMPEL, W., Arrowsmith, C.H., Edwards, A.M., BROWN, P.J., Structural Genomics Consortium (SGC)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4K8:ISOQUINOLINE-3-CARBOXYLIC+ACID'>4K8</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c6s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5c6s RCSB], [http://www.ebi.ac.uk/pdbsum/5c6s PDBsum]</span></td></tr>
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Description: Human Bromodomain and PHD Finger Containing 1, PWWP domain in complex with XST005904a
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[Category: Dong, A]]
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[[http://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref>
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[[Category: Dobrovetsky, E]]
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== References ==
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[[Category: Mader, P]]
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<references/>
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[[Category: Tempel, W]]
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__TOC__
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[[Category: Arrowsmith, C.H]]
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</StructureSection>
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[[Category: Brown, P.J]]
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[[Category: Arrowsmith, C H]]
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[[Category: BROWN, P J]]
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[[Category: DOBROVETSKY, E]]
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[[Category: DONG, A]]
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[[Category: Edwards, A M]]
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[[Category: MADER, P]]
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[[Category: Structural genomic]]
[[Category: Santhakumar, S]]
[[Category: Santhakumar, S]]
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[[Category: Edwards, A.M]]
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[[Category: TEMPEL, W]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: Histone h3 acetylation]]
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[[Category: Peregrin]]
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[[Category: Protein br140]]
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[[Category: Sgc]]
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[[Category: Transcription]]

Revision as of 14:55, 29 July 2015

Human Bromodomain and PHD Finger Containing 1, PWWP domain in complex with XST005904a

5c6s, resolution 1.30Å

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