4owp

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'''Unreleased structure'''
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==Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteosome lid.==
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<StructureSection load='4owp' size='340' side='right' caption='[[4owp]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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The entry 4owp is ON HOLD until Aug 03 2016
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4owp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OWP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OWP FirstGlance]. <br>
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Authors: Yu, Z., Mansour, W., Nakasone, M.A., Glickman, M.H., Dvir, H.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4o8x|4o8x]], [[4o8y|4o8y]]</td></tr>
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Description: Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteosome lid.
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4owp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4owp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4owp RCSB], [http://www.ebi.ac.uk/pdbsum/4owp PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Yu, Z]]
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== Function ==
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[[http://www.uniprot.org/uniprot/RPN8_YEAST RPN8_YEAST]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:9584156</ref> [[http://www.uniprot.org/uniprot/RPN11_YEAST RPN11_YEAST]] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:21075847</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Dvir, H]]
[[Category: Dvir, H]]
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[[Category: Glickman, M.H]]
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[[Category: Glickman, M H]]
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[[Category: Nakasone, M.A]]
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[[Category: Mansour, W]]
[[Category: Mansour, W]]
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[[Category: Nakasone, M A]]
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[[Category: Yu, Z]]
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[[Category: Deubiquitination]]
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[[Category: Hydrolase]]
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[[Category: Metalloprotease]]
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[[Category: Mpn domain]]
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[[Category: Proteosome]]
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[[Category: Ubiquitin]]
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[[Category: Zinc]]

Revision as of 20:08, 5 August 2015

Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteosome lid.

4owp, resolution 2.35Å

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