4uf1

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'''Unreleased structure'''
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==Deerpox virus DPV022 in complex with Bak BH3==
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<StructureSection load='4uf1' size='340' side='right' caption='[[4uf1]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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The entry 4uf1 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4uf1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UF1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UF1 FirstGlance]. <br>
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Authors: Burton, D.R., Kvansakul, M.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uf2|4uf2]], [[4uf3|4uf3]]</td></tr>
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Description: Deerpox virus DPV022 in complex with Bak BH3
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uf1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uf1 RCSB], [http://www.ebi.ac.uk/pdbsum/4uf1 PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Burton, D.R]]
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== Function ==
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[[http://www.uniprot.org/uniprot/BAK_HUMAN BAK_HUMAN]] In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.<ref>PMID:8521816</ref> <ref>PMID:17157251</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Burton, D R]]
[[Category: Kvansakul, M]]
[[Category: Kvansakul, M]]
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[[Category: Apoptosis]]
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[[Category: Bak bh3]]
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[[Category: Bcl-2]]
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[[Category: Deerpox virus]]
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[[Category: Viral protein]]

Revision as of 20:10, 5 August 2015

Deerpox virus DPV022 in complex with Bak BH3

4uf1, resolution 2.30Å

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