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4uf2

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m (Protected "4uf2" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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==Deerpox virus DPV022 in complex with Bax BH3==
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<StructureSection load='4uf2' size='340' side='right' caption='[[4uf2]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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The entry 4uf2 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4uf2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UF2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UF2 FirstGlance]. <br>
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Authors: Burton, D.R., Kvansakul, M.
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uf1|4uf1]], [[4uf3|4uf3]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uf2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uf2 RCSB], [http://www.ebi.ac.uk/pdbsum/4uf2 PDBsum]</span></td></tr>
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Description: Deerpox virus DPV022 in complex with Bax BH3
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[Category: Burton, D.R]]
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[[http://www.uniprot.org/uniprot/BAX_HUMAN BAX_HUMAN]] Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.<ref>PMID:8358790</ref> <ref>PMID:10772918</ref> <ref>PMID:8521816</ref> <ref>PMID:16113678</ref> <ref>PMID:18948948</ref> <ref>PMID:21199865</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Burton, D R]]
[[Category: Kvansakul, M]]
[[Category: Kvansakul, M]]
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[[Category: Apoptosis]]
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[[Category: Bax bh3]]
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[[Category: Bcl-2]]
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[[Category: Deerpox virus]]
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[[Category: Viral protein]]

Revision as of 20:11, 5 August 2015

Deerpox virus DPV022 in complex with Bax BH3

4uf2, resolution 3.00Å

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