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5a65
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| - | ''' | + | ==Crystal structure of mouse thiamine triphosphatase in complex with thiamine diphosphate, orthophosphate and magnesium ions.== |
| - | + | <StructureSection load='5a65' size='340' side='right' caption='[[5a65]], [[Resolution|resolution]] 1.98Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5a65]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A65 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A65 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a5y|5a5y]], [[5a60|5a60]], [[5a61|5a61]], [[5a64|5a64]], [[5a66|5a66]], [[5a67|5a67]], [[5a68|5a68]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiamine-triphosphatase Thiamine-triphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.28 3.6.1.28] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a65 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a65 RCSB], [http://www.ebi.ac.uk/pdbsum/5a65 PDBsum]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/THTPA_MOUSE THTPA_MOUSE]] Hydrolase highly specific for thiamine triphosphate (ThTP) (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Thiamine-triphosphatase]] | ||
| + | [[Category: Hothorn, M]] | ||
[[Category: Martinez, J]] | [[Category: Martinez, J]] | ||
[[Category: Truffault, V]] | [[Category: Truffault, V]] | ||
| - | [[Category: | + | [[Category: Hydrolase]] |
| + | [[Category: Triphosphate tunnel metalloenzyme]] | ||
Revision as of 20:18, 5 August 2015
Crystal structure of mouse thiamine triphosphatase in complex with thiamine diphosphate, orthophosphate and magnesium ions.
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