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5a65

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'''Unreleased structure'''
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==Crystal structure of mouse thiamine triphosphatase in complex with thiamine diphosphate, orthophosphate and magnesium ions.==
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<StructureSection load='5a65' size='340' side='right' caption='[[5a65]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
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The entry 5a65 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5a65]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A65 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A65 FirstGlance]. <br>
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Authors: Martinez, J., Truffault, V., Hothorn, M.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a5y|5a5y]], [[5a60|5a60]], [[5a61|5a61]], [[5a64|5a64]], [[5a66|5a66]], [[5a67|5a67]], [[5a68|5a68]]</td></tr>
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Description: Crystal structure of mouse thiamine triphosphatase in complex with thiamine diphosphate, orthophosphate and magnesium ions.
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiamine-triphosphatase Thiamine-triphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.28 3.6.1.28] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a65 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a65 RCSB], [http://www.ebi.ac.uk/pdbsum/5a65 PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/THTPA_MOUSE THTPA_MOUSE]] Hydrolase highly specific for thiamine triphosphate (ThTP) (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Thiamine-triphosphatase]]
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[[Category: Hothorn, M]]
[[Category: Martinez, J]]
[[Category: Martinez, J]]
[[Category: Truffault, V]]
[[Category: Truffault, V]]
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[[Category: Hothorn, M]]
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[[Category: Hydrolase]]
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[[Category: Triphosphate tunnel metalloenzyme]]

Revision as of 20:18, 5 August 2015

Crystal structure of mouse thiamine triphosphatase in complex with thiamine diphosphate, orthophosphate and magnesium ions.

5a65, resolution 1.98Å

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