4r5u
From Proteopedia
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| - | ''' | + | ==Crystal structure of Rhodostomin R46E mutant== |
| - | + | <StructureSection load='4r5u' size='340' side='right' caption='[[4r5u]], [[Resolution|resolution]] 1.81Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4r5u]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R5U FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r5r|4r5r]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r5u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r5u RCSB], [http://www.ebi.ac.uk/pdbsum/4r5u PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | + | [[http://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3). | |
| - | [[Category: Chang, Y | + | __TOC__ |
| - | [[Category: Chuang, W | + | </StructureSection> |
| - | [[Category: Huang, C | + | [[Category: Chang, Y T]] |
| - | [[Category: Shiu, J | + | [[Category: Chuang, W J]] |
| + | [[Category: Huang, C H]] | ||
| + | [[Category: Jeng, W Y]] | ||
| + | [[Category: Shiu, J H]] | ||
| + | [[Category: Disintegrin]] | ||
| + | [[Category: Integrin]] | ||
| + | [[Category: Linker region]] | ||
| + | [[Category: Rgd motif]] | ||
| + | [[Category: Rhodostomin]] | ||
| + | [[Category: Toxin]] | ||
Revision as of 13:32, 26 August 2015
Crystal structure of Rhodostomin R46E mutant
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Categories: Chang, Y T | Chuang, W J | Huang, C H | Jeng, W Y | Shiu, J H | Disintegrin | Integrin | Linker region | Rgd motif | Rhodostomin | Toxin
