4u4p
From Proteopedia
(Difference between revisions)
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- | + | ==Crystal structure of the human condensin SMC hinge domain heterodimer with short coiled coils== | |
- | + | <StructureSection load='4u4p' size='340' side='right' caption='[[4u4p]], [[Resolution|resolution]] 1.89Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4u4p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U4P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U4P FirstGlance]. <br> | |
- | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u4p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u4p RCSB], [http://www.ebi.ac.uk/pdbsum/4u4p PDBsum]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | [[ | + | [[http://www.uniprot.org/uniprot/SMC2_HUMAN SMC2_HUMAN]] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.<ref>PMID:11136719</ref> [[http://www.uniprot.org/uniprot/SMC4_HUMAN SMC4_HUMAN]] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.<ref>PMID:11136719</ref> |
- | [[ | + | == References == |
- | [[ | + | <references/> |
- | [[ | + | __TOC__ |
- | [[ | + | </StructureSection> |
- | [[ | + | [[Category: Fukakusa, S]] |
- | [[Category: | + | |
[[Category: Fukui, K]] | [[Category: Fukui, K]] | ||
- | [[Category: | + | [[Category: Hosokawa, Y]] |
- | + | ||
[[Category: Kawahara, K]] | [[Category: Kawahara, K]] | ||
+ | [[Category: Kobayashi, Y]] | ||
[[Category: Maruno, T]] | [[Category: Maruno, T]] | ||
+ | [[Category: Miyahara, Y]] | ||
+ | [[Category: Nakamura, S]] | ||
+ | [[Category: Noda, M]] | ||
+ | [[Category: Ohkubo, T]] | ||
[[Category: Oki, H]] | [[Category: Oki, H]] | ||
- | [[Category: | + | [[Category: Takino, R]] |
+ | [[Category: Uchiyama, S]] | ||
+ | [[Category: Condensin]] | ||
+ | [[Category: Protein binding]] | ||
+ | [[Category: Smc]] |
Revision as of 13:33, 26 August 2015
Crystal structure of the human condensin SMC hinge domain heterodimer with short coiled coils
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Categories: Fukakusa, S | Fukui, K | Hosokawa, Y | Kawahara, K | Kobayashi, Y | Maruno, T | Miyahara, Y | Nakamura, S | Noda, M | Ohkubo, T | Oki, H | Takino, R | Uchiyama, S | Condensin | Protein binding | Smc