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4uwt
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Hypocrea jecorina Cel7A E212Q mutant in complex with p-nitrophenyl cellobioside== |
| - | + | <StructureSection load='4uwt' size='340' side='right' caption='[[4uwt]], [[Resolution|resolution]] 1.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4uwt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UWT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UWT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NPO:P-NITROPHENOL'>NPO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase_(reducing_end) Cellulose 1,4-beta-cellobiosidase (reducing end)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.176 3.2.1.176] </span></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uwt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uwt RCSB], [http://www.ebi.ac.uk/pdbsum/4uwt PDBsum]</span></td></tr> |
| - | [[ | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GUX1_HYPJE GUX1_HYPJE]] The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Johansson, G]] | [[Category: Johansson, G]] | ||
| + | [[Category: Momeni, M H]] | ||
[[Category: Nutt, A]] | [[Category: Nutt, A]] | ||
[[Category: Stahlberg, J]] | [[Category: Stahlberg, J]] | ||
| + | [[Category: Cellulase]] | ||
| + | [[Category: Enzyme kinetic]] | ||
| + | [[Category: Glycoside hydrolase]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Non-productive binding]] | ||
Revision as of 13:34, 26 August 2015
Hypocrea jecorina Cel7A E212Q mutant in complex with p-nitrophenyl cellobioside
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