4bts
From Proteopedia
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<StructureSection load='4bts' size='340' side='right' caption='[[4bts]], [[Resolution|resolution]] 3.70Å' scene=''> | <StructureSection load='4bts' size='340' side='right' caption='[[4bts]], [[Resolution|resolution]] 3.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4bts]] is a 144 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. This structure supersedes the now removed PDB entries | + | <table><tr><td colspan='2'>[[4bts]] is a 144 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. This structure supersedes and combines the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4bpe 4bpe], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4bpn 4bpn], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4bpo 4bpo] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4bpp 4bpp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BTS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BTS FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bpe|4bpe]], [[4bpn|4bpn]], [[4bpo|4bpo]], [[4bpp|4bpp]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bpe|4bpe]], [[4bpn|4bpn]], [[4bpo|4bpo]], [[4bpp|4bpp]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bts FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bts OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bts RCSB], [http://www.ebi.ac.uk/pdbsum/4bts PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bts FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bts OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bts RCSB], [http://www.ebi.ac.uk/pdbsum/4bts PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | {{Large structure}} | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/I7MK25_TETTS I7MK25_TETTS]] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).[RuleBase:RU004365] [[http://www.uniprot.org/uniprot/E6PBR9_TETTH E6PBR9_TETTH]] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits (By similarity).[HAMAP-Rule:MF_03015] | [[http://www.uniprot.org/uniprot/I7MK25_TETTS I7MK25_TETTS]] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).[RuleBase:RU004365] [[http://www.uniprot.org/uniprot/E6PBR9_TETTH E6PBR9_TETTH]] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits (By similarity).[HAMAP-Rule:MF_03015] | ||
Revision as of 07:41, 31 August 2015
THE CRYSTAL STRUCTURE OF THE EUKARYOTIC 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH EIF1 AND EIF1A
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