4wq2
From Proteopedia
(Difference between revisions)
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- | ''' | + | ==Human calpain PEF(S) with (Z)-3-(6-bromondol-3-yl)-2-mercaptoacrylic acid bound== |
- | + | <StructureSection load='4wq2' size='340' side='right' caption='[[4wq2]], [[Resolution|resolution]] 1.64Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4wq2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WQ2 FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3SU:(2Z)-3-(6-BROMO-1H-INDOL-3-YL)-2-SULFANYLPROP-2-ENOIC+ACID'>3SU</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wq2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wq2 RCSB], [http://www.ebi.ac.uk/pdbsum/4wq2 PDBsum]</span></td></tr> | |
- | + | </table> | |
- | [[ | + | == Function == |
- | [[ | + | [[http://www.uniprot.org/uniprot/CPNS1_HUMAN CPNS1_HUMAN]] Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. |
- | [[Category: | + | __TOC__ |
- | [[Category: Allemann, R | + | </StructureSection> |
- | [[Category: Hallett, M | + | [[Category: Adams, S E]] |
- | [[Category: | + | [[Category: Allemann, R K]] |
+ | [[Category: Hallett, M B]] | ||
+ | [[Category: Miller, D J]] | ||
+ | [[Category: Rizkallah, P J]] | ||
+ | [[Category: Calcium binding]] | ||
+ | [[Category: Calpain]] | ||
+ | [[Category: Domain vi]] | ||
+ | [[Category: Ef-hand]] | ||
+ | [[Category: Human]] | ||
+ | [[Category: Hydrolase]] | ||
+ | [[Category: Protease]] |
Revision as of 12:30, 2 September 2015
Human calpain PEF(S) with (Z)-3-(6-bromondol-3-yl)-2-mercaptoacrylic acid bound
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Categories: Adams, S E | Allemann, R K | Hallett, M B | Miller, D J | Rizkallah, P J | Calcium binding | Calpain | Domain vi | Ef-hand | Human | Hydrolase | Protease