4wq2

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'''Unreleased structure'''
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==Human calpain PEF(S) with (Z)-3-(6-bromondol-3-yl)-2-mercaptoacrylic acid bound==
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<StructureSection load='4wq2' size='340' side='right' caption='[[4wq2]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
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The entry 4wq2 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4wq2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WQ2 FirstGlance]. <br>
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Authors: Adams, S.E., Rizkallah, P.J., Miller, D.J., Hallett, M.B., Allemann, R.K.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3SU:(2Z)-3-(6-BROMO-1H-INDOL-3-YL)-2-SULFANYLPROP-2-ENOIC+ACID'>3SU</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wq2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wq2 RCSB], [http://www.ebi.ac.uk/pdbsum/4wq2 PDBsum]</span></td></tr>
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Description: Human calpain PEF(S) with (Z)-3-(6-bromondol-3-yl)-2-mercaptoacrylic acid bound
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[Category: Miller, D.J]]
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[[http://www.uniprot.org/uniprot/CPNS1_HUMAN CPNS1_HUMAN]] Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
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[[Category: Rizkallah, P.J]]
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__TOC__
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[[Category: Allemann, R.K]]
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</StructureSection>
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[[Category: Hallett, M.B]]
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[[Category: Adams, S E]]
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[[Category: Adams, S.E]]
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[[Category: Allemann, R K]]
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[[Category: Hallett, M B]]
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[[Category: Miller, D J]]
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[[Category: Rizkallah, P J]]
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[[Category: Calcium binding]]
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[[Category: Calpain]]
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[[Category: Domain vi]]
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[[Category: Ef-hand]]
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[[Category: Human]]
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[[Category: Hydrolase]]
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[[Category: Protease]]

Revision as of 12:30, 2 September 2015

Human calpain PEF(S) with (Z)-3-(6-bromondol-3-yl)-2-mercaptoacrylic acid bound

4wq2, resolution 1.64Å

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