5a57
From Proteopedia
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- | ''' | + | ==The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with PUGT== |
- | + | <StructureSection load='5a57' size='340' side='right' caption='[[5a57]], [[Resolution|resolution]] 1.46Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5a57]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A57 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A57 FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5G0:(Z)-[(3R,4R,5R,6R)-3-ACETAMIDO-6-(HYDROXYMETHYL)-4,5-BIS(OXIDANYL)OXAN-2-YLIDENE]AMINO]+N-PHENYLCARBAMATE'>5G0</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr> | |
- | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a55|5a55]], [[5a56|5a56]], [[5a58|5a58]], [[5a59|5a59]], [[5a5a|5a5a]]</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a57 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a57 RCSB], [http://www.ebi.ac.uk/pdbsum/5a57 PDBsum]</span></td></tr> | |
- | [[ | + | </table> |
- | [[ | + | == Function == |
- | [[ | + | [[http://www.uniprot.org/uniprot/GH101_STRPN GH101_STRPN]] Is involved in the breakdown of mucin-type O-linked glycans. Specifically removes the T-antigen disaccharide (Gal-beta-1,3-GalNAc-alpha) from extracellular host glycoproteins. Is representative of a broadly important class of virulence factors (By similarity). |
- | [[Category: Boraston, A | + | __TOC__ |
+ | </StructureSection> | ||
+ | [[Category: Boraston, A B]] | ||
[[Category: Deng, L]] | [[Category: Deng, L]] | ||
- | [[Category: | + | [[Category: Gregg, K J]] |
+ | [[Category: Suits, M D.L]] | ||
+ | [[Category: Vocadlo, D J]] | ||
+ | [[Category: Endo-beta-n-acetylgalactosaminidase]] | ||
+ | [[Category: Gh101]] | ||
+ | [[Category: Glycoside hydrolase family 101]] | ||
+ | [[Category: Hydrolase]] | ||
+ | [[Category: Mucin degradation]] | ||
+ | [[Category: T-antigen]] |
Revision as of 12:32, 2 September 2015
The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with PUGT
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