5a57

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m (Protected "5a57" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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==The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with PUGT==
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<StructureSection load='5a57' size='340' side='right' caption='[[5a57]], [[Resolution|resolution]] 1.46&Aring;' scene=''>
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The entry 5a57 is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5a57]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A57 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A57 FirstGlance]. <br>
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Authors: Gregg, K.J., Suits, M.D.L., Deng, L., Vocadlo, D.J., Boraston, A.B.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5G0:(Z)-[(3R,4R,5R,6R)-3-ACETAMIDO-6-(HYDROXYMETHYL)-4,5-BIS(OXIDANYL)OXAN-2-YLIDENE]AMINO]+N-PHENYLCARBAMATE'>5G0</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a55|5a55]], [[5a56|5a56]], [[5a58|5a58]], [[5a59|5a59]], [[5a5a|5a5a]]</td></tr>
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Description: The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with PUGT
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a57 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a57 RCSB], [http://www.ebi.ac.uk/pdbsum/5a57 PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Suits, M.D.L]]
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== Function ==
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[[Category: Gregg, K.J]]
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[[http://www.uniprot.org/uniprot/GH101_STRPN GH101_STRPN]] Is involved in the breakdown of mucin-type O-linked glycans. Specifically removes the T-antigen disaccharide (Gal-beta-1,3-GalNAc-alpha) from extracellular host glycoproteins. Is representative of a broadly important class of virulence factors (By similarity).
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[[Category: Boraston, A.B]]
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__TOC__
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</StructureSection>
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[[Category: Boraston, A B]]
[[Category: Deng, L]]
[[Category: Deng, L]]
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[[Category: Vocadlo, D.J]]
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[[Category: Gregg, K J]]
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[[Category: Suits, M D.L]]
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[[Category: Vocadlo, D J]]
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[[Category: Endo-beta-n-acetylgalactosaminidase]]
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[[Category: Gh101]]
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[[Category: Glycoside hydrolase family 101]]
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[[Category: Hydrolase]]
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[[Category: Mucin degradation]]
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[[Category: T-antigen]]

Revision as of 12:32, 2 September 2015

The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with PUGT

5a57, resolution 1.46Å

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