5bpw
From Proteopedia
(Difference between revisions)
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- | + | ==Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain== | |
- | + | <StructureSection load='5bpw' size='340' side='right' caption='[[5bpw]], [[Resolution|resolution]] 3.40Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5bpw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BPW FirstGlance]. <br> | |
- | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5bpw RCSB], [http://www.ebi.ac.uk/pdbsum/5bpw PDBsum]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | [[ | + | [[http://www.uniprot.org/uniprot/APC4_HUMAN APC4_HUMAN]] Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.<ref>PMID:18485873</ref> |
- | [[ | + | == References == |
- | [[ | + | <references/> |
- | [[ | + | __TOC__ |
+ | </StructureSection> | ||
[[Category: Barford, D]] | [[Category: Barford, D]] | ||
+ | [[Category: Kulkarni, K]] | ||
+ | [[Category: Yang, J]] | ||
+ | [[Category: Zhang, Z]] | ||
+ | [[Category: Anaphase promoting complex]] | ||
+ | [[Category: Apc/c]] | ||
+ | [[Category: Apc4]] | ||
+ | [[Category: Cell cycle]] |
Revision as of 12:34, 2 September 2015
Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain
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Categories: Barford, D | Kulkarni, K | Yang, J | Zhang, Z | Anaphase promoting complex | Apc/c | Apc4 | Cell cycle