5cxl

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'''Unreleased structure'''
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==CRYSTAL STRUCTURE OF RTX DOMAIN BLOCK V OF ADENYLATE CYCLASE TOXIN FROM BORDETELLA PERTUSSIS==
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<StructureSection load='5cxl' size='340' side='right' caption='[[5cxl]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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The entry 5cxl is ON HOLD until Aug 26 2016
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5cxl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CXL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CXL FirstGlance]. <br>
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Authors: Motlova, L., Barinka, C., Bumba, L.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cvw|5cvw]]</td></tr>
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Description: CRYSTAL STRUCTURE OF RTX DOMAIN BLOCK V OF ADENYLATE CYCLASE TOXIN FROM BORDETELLA PERTUSSIS
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenylate_cyclase Adenylate cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.1 4.6.1.1] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cxl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5cxl RCSB], [http://www.ebi.ac.uk/pdbsum/5cxl PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CYAA_BORPE CYAA_BORPE]] This adenylate cyclase belongs to a special class of bacterial toxin. It causes whooping cough by acting on mammalian cells by elevating cAMP-concentration and thus disrupts normal cell function.
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__TOC__
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</StructureSection>
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[[Category: Adenylate cyclase]]
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[[Category: Barinka, C]]
[[Category: Bumba, L]]
[[Category: Bumba, L]]
[[Category: Motlova, L]]
[[Category: Motlova, L]]
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[[Category: Barinka, C]]
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[[Category: Calcium binding]]
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[[Category: Rtx motif]]
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[[Category: Toxin]]

Revision as of 12:35, 2 September 2015

CRYSTAL STRUCTURE OF RTX DOMAIN BLOCK V OF ADENYLATE CYCLASE TOXIN FROM BORDETELLA PERTUSSIS

5cxl, resolution 1.45Å

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