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5d69
From Proteopedia
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| - | ''' | + | ==Human calpain PEF(S) with (2Z,2Z')-2,2'-disulfanediylbis(3-(6-iodoindol-3-yl)acrylic acid) bound== |
| - | + | <StructureSection load='5d69' size='340' side='right' caption='[[5d69]], [[Resolution|resolution]] 1.97Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5d69]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D69 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D69 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=57T:(2E,2Z)-2,2-DISULFANEDIYLBIS[3-(4-IODOPHENYL)PROP-2-ENOIC+ACID]'>57T</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d69 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5d69 RCSB], [http://www.ebi.ac.uk/pdbsum/5d69 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/CPNS1_HUMAN CPNS1_HUMAN]] Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. |
| - | [[Category: Miller, D | + | __TOC__ |
| - | [[Category: Rizkallah, P | + | </StructureSection> |
| - | [[Category: | + | [[Category: Adams, S E]] |
| - | [[Category: | + | [[Category: Allemann, R K]] |
| - | [[Category: | + | [[Category: Hallett, M B]] |
| + | [[Category: Miller, D J]] | ||
| + | [[Category: Rizkallah, P J]] | ||
| + | [[Category: Robinson, E J]] | ||
| + | [[Category: Calcium binding domain]] | ||
| + | [[Category: Cysteine protease]] | ||
| + | [[Category: Domain vi]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Mercaptoacrylic acid]] | ||
Revision as of 12:35, 2 September 2015
Human calpain PEF(S) with (2Z,2Z')-2,2'-disulfanediylbis(3-(6-iodoindol-3-yl)acrylic acid) bound
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