5d69

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m (Protected "5d69" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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==Human calpain PEF(S) with (2Z,2Z')-2,2'-disulfanediylbis(3-(6-iodoindol-3-yl)acrylic acid) bound==
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<StructureSection load='5d69' size='340' side='right' caption='[[5d69]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
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The entry 5d69 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5d69]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D69 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D69 FirstGlance]. <br>
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Authors: Adams, S.E., Robinson, E.J., Rizkallah, P.J., Miller, D.J., Hallett, M.B., Allemann, R.K.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=57T:(2E,2Z)-2,2-DISULFANEDIYLBIS[3-(4-IODOPHENYL)PROP-2-ENOIC+ACID]'>57T</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d69 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5d69 RCSB], [http://www.ebi.ac.uk/pdbsum/5d69 PDBsum]</span></td></tr>
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Description:
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[Category: Robinson, E.J]]
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[[http://www.uniprot.org/uniprot/CPNS1_HUMAN CPNS1_HUMAN]] Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
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[[Category: Miller, D.J]]
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__TOC__
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[[Category: Rizkallah, P.J]]
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</StructureSection>
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[[Category: Allemann, R.K]]
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[[Category: Adams, S E]]
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[[Category: Hallett, M.B]]
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[[Category: Allemann, R K]]
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[[Category: Adams, S.E]]
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[[Category: Hallett, M B]]
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[[Category: Miller, D J]]
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[[Category: Rizkallah, P J]]
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[[Category: Robinson, E J]]
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[[Category: Calcium binding domain]]
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[[Category: Cysteine protease]]
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[[Category: Domain vi]]
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[[Category: Hydrolase]]
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[[Category: Mercaptoacrylic acid]]

Revision as of 12:35, 2 September 2015

Human calpain PEF(S) with (2Z,2Z')-2,2'-disulfanediylbis(3-(6-iodoindol-3-yl)acrylic acid) bound

5d69, resolution 1.97Å

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