1j59

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|PDB= 1j59 |SIZE=350|CAPTION= <scene name='initialview01'>1j59</scene>, resolution 2.50&Aring;
|PDB= 1j59 |SIZE=350|CAPTION= <scene name='initialview01'>1j59</scene>, resolution 2.50&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=CMP:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE'>CMP</scene>
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|LIGAND= <scene name='pdbligand=CMP:ADENOSINE-3&#39;,5&#39;-CYCLIC-MONOPHOSPHATE'>CMP</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
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[[Category: protein-dna complex]]
[[Category: protein-dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:59:06 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 12:18:14 2008''

Revision as of 10:18, 23 March 2008

Image:1j59.gif


PDB ID 1j59

Drag the structure with the mouse to rotate
, resolution 2.50Å
Ligands:
Coordinates: save as pdb, mmCIF, xml



CATABOLITE GENE ACTIVATOR PROTEIN (CAP)/DNA COMPLEX + ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE


Overview

The crystallographic structure of the CAP-DNA complex at 3.0 A resolution has been reported previously. For technical reasons, the reported structure had been determined using a gapped DNA molecule lacking two phosphates important for CAP-DNA interaction. In this work, we report the crystallographic structure of the CAP-DNA complex at 2.5 A resolution using a DNA molecule having all phosphates important for CAP-DNA interaction. The present resolution permits unambiguous identification of amino acid-base and amino acid-phosphate hydrogen bonded contacts in the CAP-DNA complex. In addition, the present resolution permits accurate definition of the kinked DNA conformation in the CAP-DNA complex.

About this Structure

1J59 is a Single protein structure of sequence from Escherichia coli. This structure supersedes the now removed PDB entry 1BER. The following page contains interesting information on the relation of 1J59 with [Catabolite Activator Protein]. Full crystallographic information is available from OCA.

Reference

Structure of the CAP-DNA complex at 2.5 angstroms resolution: a complete picture of the protein-DNA interface., Parkinson G, Wilson C, Gunasekera A, Ebright YW, Ebright RE, Berman HM, J Mol Biol. 1996 Jul 19;260(3):395-408. PMID:8757802

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