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4w63
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==TORPEDO CALIFORNICA ACETYLCHOLINESTERASE IN COMPLEX WITH A TACRINE-BENZOFURAN HYBRID INHIBITOR== |
| - | + | <StructureSection load='4w63' size='340' side='right' caption='[[4w63]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4w63]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W63 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HTB:N-(1-BENZOFURAN-2-YLMETHYL)-N-(1,2,3,4-TETRAHYDROACRIDIN-9-YL)HEPTANE-1,7-DIAMINE'>HTB</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w63 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4w63 RCSB], [http://www.ebi.ac.uk/pdbsum/4w63 PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/ACES_TORCA ACES_TORCA]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Acetylcholinesterase]] | ||
| + | [[Category: Torpedo californica]] | ||
[[Category: Lamba, D]] | [[Category: Lamba, D]] | ||
[[Category: Pesaresi, A]] | [[Category: Pesaresi, A]] | ||
| + | [[Category: Samez, S]] | ||
| + | [[Category: Benzofuran]] | ||
| + | [[Category: Enzyme-inhibitor complex]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Multitarget drug]] | ||
| + | [[Category: Tacrine]] | ||
Revision as of 11:18, 9 September 2015
TORPEDO CALIFORNICA ACETYLCHOLINESTERASE IN COMPLEX WITH A TACRINE-BENZOFURAN HYBRID INHIBITOR
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