This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4xep
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Crystal Structure of F222 form of E112A/H234A Mutant of Stationary Phase Survival Protein (SurE) from Salmonella typhimurium== |
| - | + | <StructureSection load='4xep' size='340' side='right' caption='[[4xep]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4xep]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XEP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XEP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gad|4gad]], [[4g9o|4g9o]], [[4ryt|4ryt]], [[4ryu|4ryu]], [[4xer|4xer]], [[4xgb|4xgb]], [[4xgp|4xgp]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xep OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xep RCSB], [http://www.ebi.ac.uk/pdbsum/4xep PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: Murthy, M | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/SURE_SALTY SURE_SALTY]] Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.[HAMAP-Rule:MF_00060] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Mathiharan, Y K]] | ||
| + | [[Category: Murthy, M R.N]] | ||
| + | [[Category: Domain swapping]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Phosphatase]] | ||
| + | [[Category: Rossmann fold like]] | ||
| + | [[Category: Stationary phase survival protein]] | ||
Revision as of 11:20, 9 September 2015
Crystal Structure of F222 form of E112A/H234A Mutant of Stationary Phase Survival Protein (SurE) from Salmonella typhimurium
| |||||||||||
