4xh8

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'''Unreleased structure'''
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==Crystal Structure of E112A/D230A Mutant of Stationary Phase Survival Protein (SurE) from Salmonella typhimurium==
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<StructureSection load='4xh8' size='340' side='right' caption='[[4xh8]], [[Resolution|resolution]] 3.56&Aring;' scene=''>
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The entry 4xh8 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4xh8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XH8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XH8 FirstGlance]. <br>
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Authors: Mathiharan, Y.K., Murthy, M.R.N.
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4g9o|4g9o]], [[4gad|4gad]], [[4ryt|4ryt]], [[4ryu|4ryu]], [[4xep|4xep]], [[4xer|4xer]], [[4xgb|4xgb]], [[4xgp|4xgp]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xh8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xh8 RCSB], [http://www.ebi.ac.uk/pdbsum/4xh8 PDBsum]</span></td></tr>
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Description: Crystal Structure of E112A/D230A Mutant of Stationary Phase Survival Protein (SurE) from Salmonella typhimurium
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[Category: Murthy, M.R.N]]
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[[http://www.uniprot.org/uniprot/SURE_SALTY SURE_SALTY]] Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.[HAMAP-Rule:MF_00060]
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[[Category: Mathiharan, Y.K]]
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__TOC__
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</StructureSection>
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[[Category: Mathiharan, Y K]]
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[[Category: Murthy, M R.N]]
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[[Category: Domain swapping]]
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[[Category: Hydrolase]]
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[[Category: Phosphatase]]
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[[Category: Rossmann fold like]]
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[[Category: Stationary phase survival protein]]

Revision as of 11:20, 9 September 2015

Crystal Structure of E112A/D230A Mutant of Stationary Phase Survival Protein (SurE) from Salmonella typhimurium

4xh8, resolution 3.56Å

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