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2qo1
From Proteopedia
(Difference between revisions)
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<StructureSection load='2qo1' size='340' side='right' caption='[[2qo1]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='2qo1' size='340' side='right' caption='[[2qo1]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2qo1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2qo1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QO1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QO1 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D1T:DECANE-1-THIOL'>D1T</scene>, <scene name='pdbligand=VZZ:11-[(MERCAPTOCARBONYL)OXY]UNDECANOIC+ACID'>VZZ</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D1T:DECANE-1-THIOL'>D1T</scene>, <scene name='pdbligand=VZZ:11-[(MERCAPTOCARBONYL)OXY]UNDECANOIC+ACID'>VZZ</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hzp|1hzp]], [[1u6s|1u6s]], [[1u6e|1u6e]], [[1hnj|1hnj]], [[1hnk|1hnk]], [[2qnx|2qnx]], [[2qny|2qny]], [[2qnz|2qnz]], [[2qo0|2qo0]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hzp|1hzp]], [[1u6s|1u6s]], [[1u6e|1u6e]], [[1hnj|1hnj]], [[1hnk|1hnk]], [[2qnx|2qnx]], [[2qny|2qny]], [[2qnz|2qnz]], [[2qo0|2qo0]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-acyl-carrier- | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_I Beta-ketoacyl-[acyl-carrier-protein] synthase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.41 2.3.1.41] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qo1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qo1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qo1 RCSB], [http://www.ebi.ac.uk/pdbsum/2qo1 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qo1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qo1 OCA], [http://pdbe.org/2qo1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qo1 RCSB], [http://www.ebi.ac.uk/pdbsum/2qo1 PDBsum]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2qo1" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Beta-ketoacyl-acyl-carrier-protein synthase I]] | ||
| - | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Alhamadsheh, M]] | [[Category: Alhamadsheh, M]] | ||
[[Category: Musayev, F]] | [[Category: Musayev, F]] | ||
Revision as of 03:11, 10 September 2015
2.6 Angstrom Crystal Structure of the Complex Between 11-(decyldithiocarbonyloxy)-undecanoic acid and Mycobacterium Tuberculosis FabH.
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Categories: Alhamadsheh, M | Musayev, F | Reynolds, K A | Sachdeva, S | Scarsdale, J N | Wright, H T | Acyltransferase | Enzyme inhibitor complex | Fatty acid biosynthesis | Lipid synthesis | Mechanism based inhibitor | Multifunctional enzyme | Myobacterium tuberculosis | Structural basis for substrate specificity | Substrate entry and exit | Transferase
