2m0r
From Proteopedia
(Difference between revisions)
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<StructureSection load='2m0r' size='340' side='right' caption='[[2m0r]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''> | <StructureSection load='2m0r' size='340' side='right' caption='[[2m0r]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2m0r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2m0r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M0R FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">S100A14, S100A15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">S100A14, S100A15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m0r RCSB], [http://www.ebi.ac.uk/pdbsum/2m0r PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0r OCA], [http://pdbe.org/2m0r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2m0r RCSB], [http://www.ebi.ac.uk/pdbsum/2m0r PDBsum]</span></td></tr> |
</table> | </table> | ||
| + | {{Large structure}} | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/S10AE_HUMAN S10AE_HUMAN]] Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.<ref>PMID:21559403</ref> <ref>PMID:22032898</ref> <ref>PMID:22451655</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2m0r" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Bertini, I]] | [[Category: Bertini, I]] | ||
[[Category: Borsi, V]] | [[Category: Borsi, V]] | ||
Revision as of 06:21, 10 September 2015
Solution structure and dynamics of human S100A14
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