2fra
From Proteopedia
(Difference between revisions)
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<StructureSection load='2fra' size='340' side='right' caption='[[2fra]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='2fra' size='340' side='right' caption='[[2fra]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2fra]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2fra]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FRA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FRA FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CRV:N-[1-(AMINOMETHYL)CYCLOPROPYL]-3-(BENZYLSULFONYL)-N~2~-[(1S)-2,2,2-TRIFLUORO-1-(4-HYDROXYPHENYL)ETHYL]-L-ALANINAMIDE'>CRV</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CRV:N-[1-(AMINOMETHYL)CYCLOPROPYL]-3-(BENZYLSULFONYL)-N~2~-[(1S)-2,2,2-TRIFLUORO-1-(4-HYDROXYPHENYL)ETHYL]-L-ALANINAMIDE'>CRV</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fra OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fra RCSB], [http://www.ebi.ac.uk/pdbsum/2fra PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fra OCA], [http://pdbe.org/2fra PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fra RCSB], [http://www.ebi.ac.uk/pdbsum/2fra PDBsum]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Cathepsin S]] | [[Category: Cathepsin S]] | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Somoza, J R]] | [[Category: Somoza, J R]] | ||
[[Category: Cysteine protease]] | [[Category: Cysteine protease]] | ||
Revision as of 06:35, 10 September 2015
Human Cathepsin S with CRA-27934, a Nitrile Inhibitor
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Categories: Cathepsin S | Human | Somoza, J R | Cysteine protease | Drug design | Hydrolase | Papain
