2gej
From Proteopedia
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|PDB= 2gej |SIZE=350|CAPTION= <scene name='initialview01'>2gej</scene>, resolution 2.600Å | |PDB= 2gej |SIZE=350|CAPTION= <scene name='initialview01'>2gej</scene>, resolution 2.600Å | ||
|SITE= | |SITE= | ||
- | |LIGAND= <scene name='pdbligand=GDD:GUANOSINE-5 | + | |LIGAND= <scene name='pdbligand=GDD:GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE'>GDD</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= PIMA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1772 Mycobacterium smegmatis]) | |GENE= PIMA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1772 Mycobacterium smegmatis]) | ||
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[[Category: rossmann fold]] | [[Category: rossmann fold]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:10:19 2008'' |
Revision as of 13:10, 23 March 2008
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, resolution 2.600Å | |||||||
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Ligands: | |||||||
Gene: | PIMA (Mycobacterium smegmatis) | ||||||
Coordinates: | save as pdb, mmCIF, xml |
Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP-Man
Overview
Phosphatidylinositol mannosyltransferase (PimA) is an essential enzyme for mycobacterial growth that catalyses the first mannosylation step in phosphatidyl-myo-inositol mannoside (PIM) biosynthesis. The enzyme belongs to the large GT4 family of glycosyltransferases, for which no structure is currently available. Recombinant purified PimA from Mycobacterium smegmatis has been crystallized in the presence of GDP and myo-inositol. The crystals belong to space group P2(1)2(1)2(1), with unit-cell parameters a = 37.2, b = 72.4, c = 138.2 A, and diffract to 2.4 A resolution.
About this Structure
2GEJ is a Protein complex structure of sequences from Mycobacterium smegmatis. Full crystallographic information is available from OCA.
Reference
Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis., Guerin ME, Buschiazzo A, Kordulakova J, Jackson M, Alzari PM, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 May 1;61(Pt, 5):518-20. Epub 2005 Apr 22. PMID:16511084
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