1dem

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<StructureSection load='1dem' size='340' side='right' caption='[[1dem]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
<StructureSection load='1dem' size='340' side='right' caption='[[1dem]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1dem]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dendroaspis_polylepis_polylepis Dendroaspis polylepis polylepis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DEM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DEM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1dem]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Black_mamba Black mamba]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DEM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DEM FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1den|1den]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1den|1den]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dem OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dem RCSB], [http://www.ebi.ac.uk/pdbsum/1dem PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dem OCA], [http://pdbe.org/1dem PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dem RCSB], [http://www.ebi.ac.uk/pdbsum/1dem PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IVBII_DENPO IVBII_DENPO]] Serine protease inhibitor homolog that blocks voltage-gated potassium channels (Kv1.1/KCNA1, Kv1.2/KCNA2, and Kv1.6/KCNA6) (IC(50)=0.13-50 nM).
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[[http://www.uniprot.org/uniprot/VKTH1_DENPO VKTH1_DENPO]] Serine protease inhibitor homolog that blocks voltage-gated potassium channels (Kv1.1/KCNA1, Kv1.2/KCNA2, and Kv1.6/KCNA6) (IC(50)=0.13-50 nM).<ref>PMID:8612784</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1dem" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Dendroaspis polylepis polylepis]]
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[[Category: Black mamba]]
[[Category: Foray, M F]]
[[Category: Foray, M F]]
[[Category: Lancelin, J M]]
[[Category: Lancelin, J M]]

Revision as of 20:06, 10 September 2015

PROTEINASE INHIBITOR HOMOLOGUES AS POTASSIUM CHANNEL BLOCKERS

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