2fi2

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<StructureSection load='2fi2' size='340' side='right' caption='[[2fi2]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2fi2' size='340' side='right' caption='[[2fi2]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2fi2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FI2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FI2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2fi2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FI2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FI2 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZNF42, MZF1, ZSCAN6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZNF42, MZF1, ZSCAN6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fi2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fi2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fi2 RCSB], [http://www.ebi.ac.uk/pdbsum/2fi2 PDBsum], [http://www.topsan.org/Proteins/CESG/2fi2 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fi2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fi2 OCA], [http://pdbe.org/2fi2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fi2 RCSB], [http://www.ebi.ac.uk/pdbsum/2fi2 PDBsum], [http://www.topsan.org/Proteins/CESG/2fi2 TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MZF1_HUMAN MZF1_HUMAN]] Binds to target promoter DNA and functions as trancription regulator. Regulates transcription from the PADI1 and CDH2 promoter. May be one regulator of transcriptional events during hemopoietic development.<ref>PMID:15541732</ref> <ref>PMID:17851584</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2fi2" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Peterson, F C]]
[[Category: Peterson, F C]]

Revision as of 20:49, 10 September 2015

Solution structure of the SCAN homodimer from MZF-1/ZNF42

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