2jp6

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<StructureSection load='2jp6' size='340' side='right' caption='[[2jp6]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
<StructureSection load='2jp6' size='340' side='right' caption='[[2jp6]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2jp6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Tityus_cambridgei Tityus cambridgei]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JP6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JP6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2jp6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Amazonian_scorpion Amazonian scorpion]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JP6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JP6 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jp6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jp6 RCSB], [http://www.ebi.ac.uk/pdbsum/2jp6 PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jp6 OCA], [http://pdbe.org/2jp6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jp6 RCSB], [http://www.ebi.ac.uk/pdbsum/2jp6 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/KA181_TITCA KA181_TITCA]] Reversible blocker of both Kv1.3/KCNA3 potassium channels of human T-lymphocytes (high affinity) and Shaker B potassium channels (very low affinity).<ref>PMID:12445473</ref>
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[[http://www.uniprot.org/uniprot/KA181_TITOB KA181_TITOB]] Reversible blocker of both Kv1.3/KCNA3 potassium channels (high affinity) and Shaker B (mammalian Kv1.1 analog) potassium channels (very low affinity).<ref>PMID:12445473</ref>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Tityus cambridgei]]
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[[Category: Amazonian scorpion]]
[[Category: Belluzzi, O]]
[[Category: Belluzzi, O]]
[[Category: Pertinhez, T A]]
[[Category: Pertinhez, T A]]

Revision as of 01:52, 11 September 2015

Structural and functional characterization of the recombinant form of the Kv1.3 channel blocker Tc32

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