2q87
From Proteopedia
(Difference between revisions)
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<StructureSection load='2q87' size='340' side='right' caption='[[2q87]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='2q87' size='340' side='right' caption='[[2q87]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2q87]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2q87]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q87 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Q87 FirstGlance]. <br> |
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2nms|2nms]], [[1zox|1zox]], [[1xed|1xed]], [[1hkf|1hkf]], [[2frg|2frg]], [[1smo|1smo]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2nms|2nms]], [[1zox|1zox]], [[1xed|1xed]], [[1hkf|1hkf]], [[2frg|2frg]], [[1smo|1smo]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD300A, CMRF35H ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD300A, CMRF35H ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q87 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2q87 RCSB], [http://www.ebi.ac.uk/pdbsum/2q87 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q87 OCA], [http://pdbe.org/2q87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2q87 RCSB], [http://www.ebi.ac.uk/pdbsum/2q87 PDBsum]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CLM8_HUMAN CLM8_HUMAN]] Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.<ref>PMID:10746781</ref> <ref>PMID:16339535</ref> <ref>PMID:9701027</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Dimasi, N]] | [[Category: Dimasi, N]] | ||
[[Category: Marquez, J A]] | [[Category: Marquez, J A]] | ||
Revision as of 02:05, 11 September 2015
The Crystal Structure of the Human IRp60 Ectodomain
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Categories: Human | Dimasi, N | Marquez, J A | All-beta | Cmrf35 | Ig-superfamily | Ig-v | Immune system | Immunoglobulin | Inhibitory receptor | Irem | Irp60 | Membrane protein | Myelo-monocytic cell | Natural killer cell ig-like receptor | Ncr | Negative regulation of leukocyte | Negative regulation of natural killer cell | Negative regulation of natural mast cell | Nkp44-like
