2p1z

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<StructureSection load='2p1z' size='340' side='right' caption='[[2p1z]], [[Resolution|resolution]] 2.44&Aring;' scene=''>
<StructureSection load='2p1z' size='340' side='right' caption='[[2p1z]], [[Resolution|resolution]] 2.44&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2p1z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P1Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2P1Z FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2p1z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cordi Cordi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P1Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2P1Z FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrE, DIP2097 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1717 Corynebacterium diphtheriae])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrE, DIP2097 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=257309 CORDI])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p1z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2p1z RCSB], [http://www.ebi.ac.uk/pdbsum/2p1z PDBsum], [http://www.topsan.org/Proteins/MCSG/2p1z TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p1z OCA], [http://pdbe.org/2p1z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2p1z RCSB], [http://www.ebi.ac.uk/pdbsum/2p1z PDBsum], [http://www.topsan.org/Proteins/MCSG/2p1z TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/Q6NF12_CORDI Q6NF12_CORDI]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).[HAMAP-Rule:MF_01208][SAAS:SAAS00015698]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Corynebacterium diphtheriae]]
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[[Category: Cordi]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Chang, C]]
[[Category: Chang, C]]
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[[Category: Li, H]]
[[Category: Li, H]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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[[Category: Corynebacterium diphtheriae]]
[[Category: Mcsg]]
[[Category: Mcsg]]
[[Category: Phosphoribosyltransferase]]
[[Category: Phosphoribosyltransferase]]
[[Category: PSI, Protein structure initiative]]
[[Category: PSI, Protein structure initiative]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 04:36, 11 September 2015

Crystal structure of phosphoribosyltransferase from Corynebacterium diphtheriae

2p1z, resolution 2.44Å

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