2lau
From Proteopedia
(Difference between revisions)
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<StructureSection load='2lau' size='340' side='right' caption='[[2lau]], [[NMR_Ensembles_of_Models | 19 NMR models]]' scene=''> | <StructureSection load='2lau' size='340' side='right' caption='[[2lau]], [[NMR_Ensembles_of_Models | 19 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lau]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2lau]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LAU FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">THAP11, HRIHFB2206 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">THAP11, HRIHFB2206 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lau OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lau RCSB], [http://www.ebi.ac.uk/pdbsum/2lau PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lau OCA], [http://pdbe.org/2lau PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lau RCSB], [http://www.ebi.ac.uk/pdbsum/2lau PDBsum]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/THA11_HUMAN THA11_HUMAN]] Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Campagne, S]] | [[Category: Campagne, S]] | ||
[[Category: Durand, J]] | [[Category: Durand, J]] | ||
Revision as of 06:06, 11 September 2015
Solution structure of the THAP-zinc finger domain 1-81 from the cell growth suppressor human THAP11 protein
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