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1rwv
From Proteopedia
(Difference between revisions)
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<StructureSection load='1rwv' size='340' side='right' caption='[[1rwv]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='1rwv' size='340' side='right' caption='[[1rwv]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1rwv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1rwv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RWV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RWV FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5PH:5-[5-(1-CARBOXYMETHYL-2-OXO-PROPYLCARBAMOYL)-5-PHENYL-PENTYLSULFAMOYL]-2-HYDROXY-BENZOIC+ACID'>5PH</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5PH:5-[5-(1-CARBOXYMETHYL-2-OXO-PROPYLCARBAMOYL)-5-PHENYL-PENTYLSULFAMOYL]-2-HYDROXY-BENZOIC+ACID'>5PH</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ice|1ice]], [[1bmq|1bmq]], [[1ibc|1ibc]], [[1rwk|1rwk]], [[1rwm|1rwm]], [[1rwn|1rwn]], [[1rwo|1rwo]], [[1rwp|1rwp]], [[1rww|1rww]], [[1rwx|1rwx]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ice|1ice]], [[1bmq|1bmq]], [[1ibc|1ibc]], [[1rwk|1rwk]], [[1rwm|1rwm]], [[1rwn|1rwn]], [[1rwo|1rwo]], [[1rwp|1rwp]], [[1rww|1rww]], [[1rwx|1rwx]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CASP1, IL1BC, IL1BCE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CASP1, IL1BC, IL1BCE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Caspase-1 Caspase-1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.36 3.4.22.36] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Caspase-1 Caspase-1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.36 3.4.22.36] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rwv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rwv RCSB], [http://www.ebi.ac.uk/pdbsum/1rwv PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rwv OCA], [http://pdbe.org/1rwv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1rwv RCSB], [http://www.ebi.ac.uk/pdbsum/1rwv PDBsum]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 29: | Line 29: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Caspase-1]] | [[Category: Caspase-1]] | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Brien, T O]] | [[Category: Brien, T O]] | ||
[[Category: Burdett, M T]] | [[Category: Burdett, M T]] | ||
Revision as of 12:21, 11 September 2015
Crystal structure of human caspase-1 in complex with 5-[5-(1-carboxymethyl-2-oxo-propylcarbamoyl)-5-phenyl-pentylsulfamoyl]-2-hydroxy-benzoic acid
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