1s7o

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|ACTIVITY=
|ACTIVITY=
|GENE= SPY1201, SPYM3_0842, SPS1042, SPYM18_1152 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1314 Streptococcus pyogenes])
|GENE= SPY1201, SPYM3_0842, SPS1042, SPYM18_1152 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1314 Streptococcus pyogenes])
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK00118 PRK00118]</span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s7o OCA], [http://www.ebi.ac.uk/pdbsum/1s7o PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1s7o RCSB]</span>
}}
}}
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[[Category: protein structure initiative]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: psi]]
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[[Category: putative dna binding protein; structural genomic]]
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[[Category: putative dna binding protein]]
[[Category: rna polymerase sigma factor]]
[[Category: rna polymerase sigma factor]]
[[Category: signal recognition particle]]
[[Category: signal recognition particle]]
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[[Category: structural genomic]]
[[Category: structure funded by nih]]
[[Category: structure funded by nih]]
[[Category: upf0122]]
[[Category: upf0122]]
[[Category: x-rat crystallography]]
[[Category: x-rat crystallography]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:01:32 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:04:23 2008''

Revision as of 04:04, 26 March 2008


PDB ID 1s7o

Drag the structure with the mouse to rotate
, resolution 2.31Å
Gene: SPY1201, SPYM3_0842, SPS1042, SPYM18_1152 (Streptococcus pyogenes)
Domains: PRK00118
Resources: FirstGlance, OCA, PDBsum, JenaLib, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes


Overview

The crystal structure of the putative DNA-binding protein SP_1288 (gi/15675166, also listed as gi/28895954) from Streptococcus pyogenes has been determined by X-ray crystallography to a resolution of 2.3 A using anomalous diffraction data at the Se peak wavelength. SP_1288 belongs to a family of proteins whose cellular function is associated with the signal recognition particle; no structural information has been available until now about the members of the family. Crystallographic analysis revealed that the overall fold of SP_1288 consists exclusively of alpha-helices and that 75% of the structure has good similarity to domain 4 of the sigma subunit of RNA polymerase. This suggests its possible involvement in the biochemical function of transcription initiation, which includes interaction with DNA.

About this Structure

1S7O is a Single protein structure of sequence from Streptococcus pyogenes. Full crystallographic information is available from OCA.

Reference

Structure of the putative DNA-binding protein SP_1288 from Streptococcus pyogenes., Oganesyan V, Pufan R, DeGiovanni A, Yokota H, Kim R, Kim SH, Acta Crystallogr D Biol Crystallogr. 2004 Jul;60(Pt 7):1266-71. Epub 2004, Jun 22. PMID:15213388

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