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2l4n
From Proteopedia
(Difference between revisions)
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<StructureSection load='2l4n' size='340' side='right' caption='[[2l4n]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2l4n' size='340' side='right' caption='[[2l4n]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2l4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2l4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L4N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2L4N FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CCL21, RP11-195F19.22-001, SCYA21, UNQ784/PRO1600 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CCL21, RP11-195F19.22-001, SCYA21, UNQ784/PRO1600 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2l4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l4n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2l4n RCSB], [http://www.ebi.ac.uk/pdbsum/2l4n PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2l4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l4n OCA], [http://pdbe.org/2l4n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2l4n RCSB], [http://www.ebi.ac.uk/pdbsum/2l4n PDBsum]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CCL21_HUMAN CCL21_HUMAN]] Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Love, M]] | [[Category: Love, M]] | ||
[[Category: Peterson, F C]] | [[Category: Peterson, F C]] | ||
Revision as of 15:38, 11 September 2015
Solution Structure of the Chemokine CCL21
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Categories: Human | Love, M | Peterson, F C | Sandberg, J L | Veldkamp, C T | Ccr7 | Chemokine | Cytokine | Exodus-2 | Slc
