2gsh
From Proteopedia
(Difference between revisions)
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<StructureSection load='2gsh' size='340' side='right' caption='[[2gsh]], [[Resolution|resolution]] 2.39Å' scene=''> | <StructureSection load='2gsh' size='340' side='right' caption='[[2gsh]], [[Resolution|resolution]] 2.39Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2gsh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2gsh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GSH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GSH FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STM2291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STM2291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-rhamnonate_dehydratase L-rhamnonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.90 4.2.1.90] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-rhamnonate_dehydratase L-rhamnonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.90 4.2.1.90] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gsh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gsh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gsh RCSB], [http://www.ebi.ac.uk/pdbsum/2gsh PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2gsh TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gsh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gsh OCA], [http://pdbe.org/2gsh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gsh RCSB], [http://www.ebi.ac.uk/pdbsum/2gsh PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2gsh TOPSAN]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RHMD_SALTY RHMD_SALTY]] Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR). Can also dehydrate L-lyxonate and L-mannonate, although less efficiently, but not 2-keto-4-hydroxyheptane-1,7-dioate.<ref>PMID:18754693</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: L-rhamnonate dehydratase]] | [[Category: L-rhamnonate dehydratase]] | ||
| - | [[Category: | + | [[Category: Salty]] |
[[Category: Adams, J M]] | [[Category: Adams, J M]] | ||
[[Category: Almo, S C]] | [[Category: Almo, S C]] | ||
Revision as of 01:12, 12 September 2015
Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium
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Categories: L-rhamnonate dehydratase | Salty | Adams, J M | Almo, S C | Burley, S K | Dickey, M | Gerlt, J | Malashkevich, V N | Structural genomic | Patskovsky, Y | Sauder, J M | Wasserman, S R | Enolase | Lyase | NYSGXRC, New York SGX Research Center for Structural Genomics | PSI, Protein structure initiative
