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| - | ==Crystal structure of human aspartate beta-hydroxylase isoform a==
| + | #REDIRECT [[5apa]] This PDB entry is obsolete and replaced by 5apa |
| - | <StructureSection load='3rcq' size='340' side='right' caption='[[3rcq]], [[Resolution|resolution]] 2.05Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[3rcq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RCQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RCQ FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ASPH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide-aspartate_beta-dioxygenase Peptide-aspartate beta-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.11.16 1.14.11.16] </span></td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rcq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rcq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rcq RCSB], [http://www.ebi.ac.uk/pdbsum/3rcq PDBsum]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[http://www.uniprot.org/uniprot/ASPH_HUMAN ASPH_HUMAN]] Isoform 1: specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins.<ref>PMID:22586105</ref> Isoform 8: membrane-bound Ca(2+)-sensing protein, which is a structural component of the ER-plasma membrane junctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cells.<ref>PMID:22586105</ref>
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| - | == References ==
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| - | <references/>
| + | |
| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Homo sapiens]]
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| - | [[Category: Peptide-aspartate beta-dioxygenase]]
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| - | [[Category: Allerston, C K]]
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| - | [[Category: Arrowsmith, C H]]
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| - | [[Category: Bountra, C]]
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| - | [[Category: Bray, J]]
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| - | [[Category: Chaikuad, A]]
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| - | [[Category: Delft, F von]]
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| - | [[Category: Edwards, A]]
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| - | [[Category: Gileadi, O]]
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| - | [[Category: Hozjan, V]]
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| - | [[Category: Kavanagh, K]]
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| - | [[Category: Kochan, G]]
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| - | [[Category: Krojer, T]]
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| - | [[Category: Muniz, J R]]
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| - | [[Category: Oppermann, U]]
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| - | [[Category: Pilka, E]]
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| - | [[Category: Structural genomic]]
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| - | [[Category: Weigelt, J]]
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| - | [[Category: Aspartate beta-hydroxylase isoform some]]
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| - | [[Category: Human]]
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| - | [[Category: Oxidoreductase]]
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| - | [[Category: Sgc]]
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