4u6o
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==STRUCTURE OF THE CAP-BINDING DOMAIN OF INFLUENZA VIRUS POLYMERASE SUBUNIT PB2== |
| - | + | <StructureSection load='4u6o' size='340' side='right' caption='[[4u6o]], [[Resolution|resolution]] 1.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4u6o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U6O FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u6o OCA], [http://pdbe.org/4u6o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u6o RCSB], [http://www.ebi.ac.uk/pdbsum/4u6o PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/PB2_I34A1 PB2_I34A1]] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity). |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Fukushima, K]] | [[Category: Fukushima, K]] | ||
| + | [[Category: Takimoto-Kamimura, M]] | ||
| + | [[Category: Cap-binding domain]] | ||
| + | [[Category: Influenza virus]] | ||
| + | [[Category: Pb2 subunit]] | ||
| + | [[Category: Rna-dependent rna polymerase]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 13:49, 7 October 2015
STRUCTURE OF THE CAP-BINDING DOMAIN OF INFLUENZA VIRUS POLYMERASE SUBUNIT PB2
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