4v1d

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'''Unreleased structure'''
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==Ternary complex among two human derived single chain antibody fragments and Cn2 toxin from scorpion Centruroides noxius.==
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<StructureSection load='4v1d' size='340' side='right' caption='[[4v1d]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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The entry 4v1d is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4v1d]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Centruroides_noxius Centruroides noxius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V1D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V1D FirstGlance]. <br>
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Authors: RIANO-UMBARILA, L., SERRANO-POSADA, H., ROJAS-TREJO, S., RUDINO-PINERA, E., BECERRIL, B.
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v1d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v1d OCA], [http://pdbe.org/4v1d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4v1d RCSB], [http://www.ebi.ac.uk/pdbsum/4v1d PDBsum]</span></td></tr>
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</table>
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Description: Ternary complex among two human derived single chain antibody fragments and Cn2 toxin from scorpion Centruroides noxius.
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== Function ==
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[[Category: Unreleased Structures]]
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[[http://www.uniprot.org/uniprot/SCX2_CENNO SCX2_CENNO]] Mammal beta-toxins bind voltage-independently at site-4 of sodium channels and shift the activation voltage to more negative potentials. This toxin is active against mammals.
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__TOC__
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</StructureSection>
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[[Category: Centruroides noxius]]
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[[Category: Becerril, B]]
[[Category: Riano-Umbarila, L]]
[[Category: Riano-Umbarila, L]]
[[Category: Rojas-Trejo, S]]
[[Category: Rojas-Trejo, S]]
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[[Category: Becerril, B]]
 
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[[Category: Serrano-Posada, H]]
 
[[Category: Rudino-Pinera, E]]
[[Category: Rudino-Pinera, E]]
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[[Category: Serrano-Posada, H]]
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[[Category: Cn2 toxin]]
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[[Category: Directed evolution]]
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[[Category: Human scfv]]
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[[Category: Scorpion venom neutralization]]
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[[Category: Toxin-immune system complex]]

Revision as of 13:49, 7 October 2015

Ternary complex among two human derived single chain antibody fragments and Cn2 toxin from scorpion Centruroides noxius.

4v1d, resolution 3.10Å

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