This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5d5n
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Crystal Structure of the Human Cytomegalovirus pUL50-pUL53 Complex== |
| - | + | <StructureSection load='5d5n' size='340' side='right' caption='[[5d5n]], [[Resolution|resolution]] 2.44Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5d5n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D5N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D5N FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d5n OCA], [http://pdbe.org/5d5n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d5n RCSB], [http://www.ebi.ac.uk/pdbsum/5d5n PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/UL50_HCMVA UL50_HCMVA]] Plays a major role in virion nuclear egress, the first step of virion release from infected cell. Viral capsids are initially assembled within the nucleus, UL53/UL50 complex induces capsids budding and envelopment into the perinuclear space. Then UL53/UL50 complex promotes fusion of perinuclear virion envelope with the outer nuclear membrane, releasing viral capsid into the cytoplasm where it will engages budding sites in the Golgi or trans-Golgi network (By similarity). [[http://www.uniprot.org/uniprot/UL53_HCMVA UL53_HCMVA]] Plays a major role in virion nuclear egress, the first step of virion release from infected cell. Viral capsids are initially assembled within the nucleus, UL53/UL50 complex induces capsids budding and envelopment into the perinuclear space. Then UL53/UL50 complex promotes fusion of perinuclear virion envelope with the outer nuclear membrane, releasing viral capsid into the cytoplasm where it will engages budding sites in the Golgi or trans-Golgi network (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Egerer-Sieber, C]] | [[Category: Egerer-Sieber, C]] | ||
| - | [[Category: Walzer, S.A]] | ||
| - | [[Category: Sevvana, M]] | ||
| - | [[Category: Muller, Y.A]] | ||
[[Category: Hohl, K]] | [[Category: Hohl, K]] | ||
| + | [[Category: Muller, Y A]] | ||
| + | [[Category: Sevvana, M]] | ||
| + | [[Category: Walzer, S A]] | ||
| + | [[Category: Viral nuclear egress complex]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 13:53, 7 October 2015
Crystal Structure of the Human Cytomegalovirus pUL50-pUL53 Complex
| |||||||||||
