5d5n
From Proteopedia
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| - | ''' | + | ==Crystal Structure of the Human Cytomegalovirus pUL50-pUL53 Complex== |
| - | + | <StructureSection load='5d5n' size='340' side='right' caption='[[5d5n]], [[Resolution|resolution]] 2.44Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5d5n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D5N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D5N FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d5n OCA], [http://pdbe.org/5d5n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d5n RCSB], [http://www.ebi.ac.uk/pdbsum/5d5n PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/UL50_HCMVA UL50_HCMVA]] Plays a major role in virion nuclear egress, the first step of virion release from infected cell. Viral capsids are initially assembled within the nucleus, UL53/UL50 complex induces capsids budding and envelopment into the perinuclear space. Then UL53/UL50 complex promotes fusion of perinuclear virion envelope with the outer nuclear membrane, releasing viral capsid into the cytoplasm where it will engages budding sites in the Golgi or trans-Golgi network (By similarity). [[http://www.uniprot.org/uniprot/UL53_HCMVA UL53_HCMVA]] Plays a major role in virion nuclear egress, the first step of virion release from infected cell. Viral capsids are initially assembled within the nucleus, UL53/UL50 complex induces capsids budding and envelopment into the perinuclear space. Then UL53/UL50 complex promotes fusion of perinuclear virion envelope with the outer nuclear membrane, releasing viral capsid into the cytoplasm where it will engages budding sites in the Golgi or trans-Golgi network (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Egerer-Sieber, C]] | [[Category: Egerer-Sieber, C]] | ||
| - | [[Category: Walzer, S.A]] | ||
| - | [[Category: Sevvana, M]] | ||
| - | [[Category: Muller, Y.A]] | ||
[[Category: Hohl, K]] | [[Category: Hohl, K]] | ||
| + | [[Category: Muller, Y A]] | ||
| + | [[Category: Sevvana, M]] | ||
| + | [[Category: Walzer, S A]] | ||
| + | [[Category: Viral nuclear egress complex]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 13:53, 7 October 2015
Crystal Structure of the Human Cytomegalovirus pUL50-pUL53 Complex
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