RNA polymerase
From Proteopedia
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{{STRUCTURE_3m3y| PDB=3m3y | SIZE=400| SCENE=RNA_polymerase/Cv/1 |right|CAPTION=Yeast RNA polymerase II elongation complex C complexed with DNA and RNA and Zn+2 (grey) and Mg+2 (green) ions [[3m3y]]. Subunit B1 (grey), B2 (green), B3 (pink), B9 (wheat), B11 (rust), ABC1 (magenta), ABC2 (cyan), ABC3 (red), ABC4 (aqua), ABC5 (blue). }} | {{STRUCTURE_3m3y| PDB=3m3y | SIZE=400| SCENE=RNA_polymerase/Cv/1 |right|CAPTION=Yeast RNA polymerase II elongation complex C complexed with DNA and RNA and Zn+2 (grey) and Mg+2 (green) ions [[3m3y]]. Subunit B1 (grey), B2 (green), B3 (pink), B9 (wheat), B11 (rust), ABC1 (magenta), ABC2 (cyan), ABC3 (red), ABC4 (aqua), ABC5 (blue). }} | ||
| - | '''RNA polymerase''' (RNAP, '''DNA primase''', dnaG) catalyzes the addition of nucleotides to RNA during transcription. The DNA-dependent eukaryote RNAP are divided to RNAP I (or '''Pol I''') which transcribes ribosomal RNA; RNAP II (or '''Pol II''') transcribes DNA and most snRNA and microRNA; RNAP III (or '''Pol III''') transcribes tRNA and 5S ribosomal RNA.DNA primase (DNAP) is RNAP which catalyzes the synthesis of the RNA primer which complements an ssDNA template and initiates DNA synthesis. | + | '''RNA polymerase''' (RNAP, '''DNA primase''', dnaG) catalyzes the addition of nucleotides to RNA during transcription.<br /> |
| - | For RNA polymerase | + | '''DNA-dependent RNA polymerase''' catalyzes the transcription of RNA from a DNA template. The DNA-dependent eukaryote RNAP are divided to<br /> |
| + | '''RNAP I''' (or '''Pol I''') which transcribes ribosomal RNA; <br /> | ||
| + | '''RNAP II''' (or '''Pol II''') transcribes DNA and most snRNA and microRNA; <br /> | ||
| + | '''RNAP III''' (or '''Pol III''') transcribes tRNA and 5S ribosomal RNA.<br /> | ||
| + | '''DNA primase''' (DNAP) is RNAP which catalyzes the synthesis of the RNA primer which complements an ssDNA template and initiates DNA synthesis. <br /> | ||
| + | '''dnaG''' is a bacterial primase.<br /> | ||
| + | For DNA-dependent RNA polymerase see<br /> | ||
* [[Molecular Playground/T7 RNAP Conformations]]<br /> | * [[Molecular Playground/T7 RNAP Conformations]]<br /> | ||
* [[User:Luis E Ramirez-Tapia/T7 RNA polymerase]]<br /> | * [[User:Luis E Ramirez-Tapia/T7 RNA polymerase]]<br /> | ||
* [[Molecular Playground/T7 RNA Polymerase (7 mer int)]].<br /> | * [[Molecular Playground/T7 RNA Polymerase (7 mer int)]].<br /> | ||
| + | * [[Molecular Playground/Human mtRNA pol]].<br /> | ||
| + | |||
| + | '''RNA-dependent RNA polymerase''' catalyzes the replication of RNA from a RNA template. An example is the '''Influenza virus RNA polymerase''' which is composed of 3 subunits. Subunit '''PA''' is involved in cap-snatching. Subunit '''PB1''' is involved in RNA synthesis. Subunit '''PB2''' is involved in RNA replication and transcription. It is implicated in endonuclease cleavage of RNA primers. <scene name='1qln/Rockets_steitz_colors/1'>View of the nucleic acid</scene> ([[1qln]]; blue: nontemplate strand; cyan: template strand; red:RNA). See also [[Transcription and RNA Processing]].<br /> | ||
For RNA-dependent RNA polymerase from Hepatitis C virus - NS5B - see<br /> | For RNA-dependent RNA polymerase from Hepatitis C virus - NS5B - see<br /> | ||
* [[NS5B]].<br /> | * [[NS5B]].<br /> | ||
| - | For DNA-dependent RNA polymerase see<br /> | ||
| - | * [[Molecular Playground/Human mtRNA pol]].<br /> | ||
| - | For the ''Thermus thermophilus'' β' subunit see<br /> | ||
| - | * [[Beta-Prime Subunit of Bacterial RNA Polymerase]]<br /> | ||
| - | For the influenza virus RNA-dependent RNA polymerase PB2 and PA homology model and sequence alignment see<br /> | ||
* [[User:Michael Strong/H1N1/PB2]]<br /> | * [[User:Michael Strong/H1N1/PB2]]<br /> | ||
* [[User:Michael Strong/H1N1/PB2/MSA]]<br /> | * [[User:Michael Strong/H1N1/PB2/MSA]]<br /> | ||
* [[User:Michael Strong/H1N1/PA]]<br /> | * [[User:Michael Strong/H1N1/PA]]<br /> | ||
* [[User:Michael Strong/H1N1/PA/MSA]] | * [[User:Michael Strong/H1N1/PA/MSA]] | ||
| + | |||
| + | For the ''Thermus thermophilus'' β' subunit see<br /> | ||
| + | * [[Beta-Prime Subunit of Bacterial RNA Polymerase]]<br /> | ||
== 3D Structures of RNA polymerase == | == 3D Structures of RNA polymerase == | ||
Revision as of 09:44, 14 October 2015
RNA polymerase (RNAP, DNA primase, dnaG) catalyzes the addition of nucleotides to RNA during transcription.
DNA-dependent RNA polymerase catalyzes the transcription of RNA from a DNA template. The DNA-dependent eukaryote RNAP are divided to
RNAP I (or Pol I) which transcribes ribosomal RNA;
RNAP II (or Pol II) transcribes DNA and most snRNA and microRNA;
RNAP III (or Pol III) transcribes tRNA and 5S ribosomal RNA.
DNA primase (DNAP) is RNAP which catalyzes the synthesis of the RNA primer which complements an ssDNA template and initiates DNA synthesis.
dnaG is a bacterial primase.
For DNA-dependent RNA polymerase see
- Molecular Playground/T7 RNAP Conformations
- User:Luis E Ramirez-Tapia/T7 RNA polymerase
- Molecular Playground/T7 RNA Polymerase (7 mer int).
- Molecular Playground/Human mtRNA pol.
RNA-dependent RNA polymerase catalyzes the replication of RNA from a RNA template. An example is the Influenza virus RNA polymerase which is composed of 3 subunits. Subunit PA is involved in cap-snatching. Subunit PB1 is involved in RNA synthesis. Subunit PB2 is involved in RNA replication and transcription. It is implicated in endonuclease cleavage of RNA primers. (1qln; blue: nontemplate strand; cyan: template strand; red:RNA). See also Transcription and RNA Processing.
For RNA-dependent RNA polymerase from Hepatitis C virus - NS5B - see
- NS5B.
- User:Michael Strong/H1N1/PB2
- User:Michael Strong/H1N1/PB2/MSA
- User:Michael Strong/H1N1/PA
- User:Michael Strong/H1N1/PA/MSA
For the Thermus thermophilus β' subunit see
3D Structures of RNA polymerase
Updated on 14-October-2015
- Created with the participation of Craig T Martin.
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Karsten Theis
