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5e0a
From Proteopedia
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| - | + | ==Crystal Structure of the complex of Camel Peptidoglycan Recognition Protein (CPGRP-S) and N-Acetylglucosamine at 2.6 A== | |
| - | + | <StructureSection load='5e0a' size='340' side='right' caption='[[5e0a]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5e0a]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ebt 4ebt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E0A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E0A FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nw3|3nw3]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e0a OCA], [http://pdbe.org/5e0a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e0a RCSB], [http://www.ebi.ac.uk/pdbsum/5e0a PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR]] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity). |
| - | [[ | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Camelus dromedarius]] | ||
[[Category: Dube, D]] | [[Category: Dube, D]] | ||
| - | [[Category: Sharma, S]] | ||
[[Category: Kaur, P]] | [[Category: Kaur, P]] | ||
| + | [[Category: Sharma, P]] | ||
| + | [[Category: Sharma, S]] | ||
| + | [[Category: Singh, T P]] | ||
| + | [[Category: Sinha, M]] | ||
| + | [[Category: Antibiotic]] | ||
| + | [[Category: Antimicrobial]] | ||
| + | [[Category: Immune response]] | ||
| + | [[Category: Immune system]] | ||
| + | [[Category: Nag]] | ||
| + | [[Category: Peptidoglycan binding]] | ||
| + | [[Category: Pgrp]] | ||
| + | [[Category: Secreted]] | ||
Revision as of 04:10, 16 October 2015
Crystal Structure of the complex of Camel Peptidoglycan Recognition Protein (CPGRP-S) and N-Acetylglucosamine at 2.6 A
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Categories: Camelus dromedarius | Dube, D | Kaur, P | Sharma, P | Sharma, S | Singh, T P | Sinha, M | Antibiotic | Antimicrobial | Immune response | Immune system | Nag | Peptidoglycan binding | Pgrp | Secreted
