5e0b
From Proteopedia
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| - | + | ==Crystal structure of the complex of Peptidoglycan recognition protein PGRP-S with N-Acetyl Muramic acid at 2.6 A resolution== | |
| - | + | <StructureSection load='5e0b' size='340' side='right' caption='[[5e0b]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5e0b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E0B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E0B FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMU:BETA-N-ACETYLMURAMIC+ACID'>AMU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e0b OCA], [http://pdbe.org/5e0b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e0b RCSB], [http://www.ebi.ac.uk/pdbsum/5e0b PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR]] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity). |
| - | [[ | + | __TOC__ |
| - | [[ | + | </StructureSection> |
| - | [[Category: | + | [[Category: Camelus dromedarius]] |
[[Category: Dube, D]] | [[Category: Dube, D]] | ||
| - | [[Category: Sharma, S]] | ||
[[Category: Kaur, P]] | [[Category: Kaur, P]] | ||
| + | [[Category: Sharma, P]] | ||
| + | [[Category: Sharma, S]] | ||
| + | [[Category: Singh, T P]] | ||
| + | [[Category: Sinha, M]] | ||
| + | [[Category: Yamini, S]] | ||
| + | [[Category: Immune system]] | ||
| + | [[Category: N-acetyl muramic acid]] | ||
| + | [[Category: Peptidoglycan]] | ||
Revision as of 04:10, 16 October 2015
Crystal structure of the complex of Peptidoglycan recognition protein PGRP-S with N-Acetyl Muramic acid at 2.6 A resolution
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