12-oxophytodienoate reductase

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<StructureSection load='1icq' size='340' side='right' caption='Tomato OPR1 complex with FMN and 12-oxophytodienoate (PDB code [[1icq]])' scene='71/710043/Cv/1'>
<StructureSection load='1icq' size='340' side='right' caption='Tomato OPR1 complex with FMN and 12-oxophytodienoate (PDB code [[1icq]])' scene='71/710043/Cv/1'>
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'''12-oxophytodienoate reductase''' (OPR) catalyzes the conversion of 12-oxophytodienoate to 3-oxo-pentenyl-cyclopentane octanoate. The expression of OPR is induced by stimuli like touch, wind, wounding, UV light and detergent. OPR uses the cofactor flavin mononucleotide (FMN) which is reduced by NADPH. OPR exhibits self inhibition by dimerization. Three isozymes of OPR are known – OPR1, OPR2, OPR3.<br />
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'''12-oxophytodienoate reductase''' (OPR) catalyzes the conversion of <scene name='71/710043/Cv/2'>12-oxophytodienoate</scene> to 3-oxo-pentenyl-cyclopentane octanoate. The expression of OPR is induced by stimuli like touch, wind, wounding, UV light and detergent. OPR uses the cofactor flavin mononucleotide (FMN) which is reduced by NADPH. OPR exhibits self inhibition by dimerization. Three isozymes of OPR are known – OPR1, OPR2, OPR3.<br />
* OPR1 cleaves olefinic bonds in α,β-unsaturated carbonyls.<br />
* OPR1 cleaves olefinic bonds in α,β-unsaturated carbonyls.<br />
* OPR3 cleaves olefinic bonds in cyclic enones.
* OPR3 cleaves olefinic bonds in cyclic enones.

Revision as of 11:36, 21 October 2015

Tomato OPR1 complex with FMN and 12-oxophytodienoate (PDB code 1icq)

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3D Structures of 12-oxophytodienoate reductase

Updated on 21-October-2015

References

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Alexander Berchansky, Michal Harel, Joel L. Sussman

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