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Cluster of Differentiation CD38

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{{STRUCTURE_3gc6| PDB=3gc6 | SIZE=400| SCENE=Cluster_of_Differentiation_38/Cv/1 |right|CAPTION=Glycosylated Cluster of Differentiation 38 (CD38) complex with sulfate [[3gc6]] }}
{{STRUCTURE_3gc6| PDB=3gc6 | SIZE=400| SCENE=Cluster_of_Differentiation_38/Cv/1 |right|CAPTION=Glycosylated Cluster of Differentiation 38 (CD38) complex with sulfate [[3gc6]] }}
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[[Cluster of Differentiation 38]] (CD38), known also as ''ADP-ribosyl cyclase 1'' (ADPRC1), catalyzes the synthesis and hydrolysis of cyclic ADP-ribose from NAD+ to ADP-ribose (ADPR). It is found on the surface of immune cells. It also functions in cell adhesion, signal transduction and Ca++ signaling.
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[[Cluster of Differentiation 38]] (CD38), known also as ''ADP-ribosyl cyclase 1'' (ADPRC1), catalyzes the synthesis and hydrolysis of cyclic ADP-ribose from NAD+ to ADP-ribose (ADPR). It is found on the surface of immune cells. It also functions in cell adhesion, signal transduction and Ca++ signaling. '''ADP-ribosyl cyclase''' (ADPRC) is the ''Aplysia californica'' homolog of CD38. It catalyzes the synthesis and hydrolysis of cyclic ADP-ribose. It uses NAD+ as substrate and produces cyclic ADP-ribose (cADPR).
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**[[3rop]] - hCD38 (mutant) + arabinitol derivative + nicotinamide<br />
**[[3rop]] - hCD38 (mutant) + arabinitol derivative + nicotinamide<br />
**[[3p5s]] - bADPRC + arabinitol derivative<br />
**[[3p5s]] - bADPRC + arabinitol derivative<br />
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*ADPRC
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**[[1r12]] - AcADPRC - ''Aplysia californica''<br />
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**[[1r0s]] – AcADPRC (mutant) <br />
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*ADPRC+ligand
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**[[1r15]] - AcADPRC+nicotinamide<br />
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**[[3i9j]] – AcADPRC+nicotinamide+2F-NAD+2F-ADPRI<br />
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**[[3i9k]] – AcADPRC (mutant)+NAD<br />
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**[[3i9l]] – AcADPRC (mutant)+N1-CIDPR<br />
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**[[3i9o]] – AcADPRC+Ribosyl-2F-ADPR<br />
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**[[3zwx]], [[3zwy]] – AcADPRC + 8-Br-ADPR<br />
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**[[1r16]] - AcADPRC+3-pyridinylcarbinol<br />
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**[[3zwm]] – AcADPRC + NAD + cADPR<br />
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**[[3zwn]] – AcADPRC + NGD + cGDPR<br />
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**[[3zwo]] – AcADPRC + NGD + GDPR<br />
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**[[3zwp]], [[3zwv]], [[3zww]] – AcADPRC+ diphosphate ribosyl ara-2F-ADPR<br />
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}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:39, 28 October 2015

Template:STRUCTURE 3gc6

Cluster of Differentiation 38 (CD38), known also as ADP-ribosyl cyclase 1 (ADPRC1), catalyzes the synthesis and hydrolysis of cyclic ADP-ribose from NAD+ to ADP-ribose (ADPR). It is found on the surface of immune cells. It also functions in cell adhesion, signal transduction and Ca++ signaling. ADP-ribosyl cyclase (ADPRC) is the Aplysia californica homolog of CD38. It catalyzes the synthesis and hydrolysis of cyclic ADP-ribose. It uses NAD+ as substrate and produces cyclic ADP-ribose (cADPR).

Contents

3D Structures of Cluster of Differentiation 38

Updated on 28-October-2015

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky

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