Cluster of Differentiation CD38
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_3gc6| PDB=3gc6 | SIZE=400| SCENE=Cluster_of_Differentiation_38/Cv/1 |right|CAPTION=Glycosylated Cluster of Differentiation 38 (CD38) complex with sulfate [[3gc6]] }} | {{STRUCTURE_3gc6| PDB=3gc6 | SIZE=400| SCENE=Cluster_of_Differentiation_38/Cv/1 |right|CAPTION=Glycosylated Cluster of Differentiation 38 (CD38) complex with sulfate [[3gc6]] }} | ||
| - | [[Cluster of Differentiation 38]] (CD38), known also as ''ADP-ribosyl cyclase 1'' (ADPRC1), catalyzes the synthesis and hydrolysis of cyclic ADP-ribose from NAD+ to ADP-ribose (ADPR). It is found on the surface of immune cells. It also functions in cell adhesion, signal transduction and Ca++ signaling. | + | [[Cluster of Differentiation 38]] (CD38), known also as ''ADP-ribosyl cyclase 1'' (ADPRC1), catalyzes the synthesis and hydrolysis of cyclic ADP-ribose from NAD+ to ADP-ribose (ADPR). It is found on the surface of immune cells. It also functions in cell adhesion, signal transduction and Ca++ signaling. '''ADP-ribosyl cyclase''' (ADPRC) is the ''Aplysia californica'' homolog of CD38. It catalyzes the synthesis and hydrolysis of cyclic ADP-ribose. It uses NAD+ as substrate and produces cyclic ADP-ribose (cADPR). |
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**[[3rop]] - hCD38 (mutant) + arabinitol derivative + nicotinamide<br /> | **[[3rop]] - hCD38 (mutant) + arabinitol derivative + nicotinamide<br /> | ||
**[[3p5s]] - bADPRC + arabinitol derivative<br /> | **[[3p5s]] - bADPRC + arabinitol derivative<br /> | ||
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| + | *ADPRC | ||
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| + | **[[1r12]] - AcADPRC - ''Aplysia californica''<br /> | ||
| + | **[[1r0s]] – AcADPRC (mutant) <br /> | ||
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| + | *ADPRC+ligand | ||
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| + | **[[1r15]] - AcADPRC+nicotinamide<br /> | ||
| + | **[[3i9j]] – AcADPRC+nicotinamide+2F-NAD+2F-ADPRI<br /> | ||
| + | **[[3i9k]] – AcADPRC (mutant)+NAD<br /> | ||
| + | **[[3i9l]] – AcADPRC (mutant)+N1-CIDPR<br /> | ||
| + | **[[3i9o]] – AcADPRC+Ribosyl-2F-ADPR<br /> | ||
| + | **[[3zwx]], [[3zwy]] – AcADPRC + 8-Br-ADPR<br /> | ||
| + | **[[1r16]] - AcADPRC+3-pyridinylcarbinol<br /> | ||
| + | **[[3zwm]] – AcADPRC + NAD + cADPR<br /> | ||
| + | **[[3zwn]] – AcADPRC + NGD + cGDPR<br /> | ||
| + | **[[3zwo]] – AcADPRC + NGD + GDPR<br /> | ||
| + | **[[3zwp]], [[3zwv]], [[3zww]] – AcADPRC+ diphosphate ribosyl ara-2F-ADPR<br /> | ||
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}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:39, 28 October 2015
Cluster of Differentiation 38 (CD38), known also as ADP-ribosyl cyclase 1 (ADPRC1), catalyzes the synthesis and hydrolysis of cyclic ADP-ribose from NAD+ to ADP-ribose (ADPR). It is found on the surface of immune cells. It also functions in cell adhesion, signal transduction and Ca++ signaling. ADP-ribosyl cyclase (ADPRC) is the Aplysia californica homolog of CD38. It catalyzes the synthesis and hydrolysis of cyclic ADP-ribose. It uses NAD+ as substrate and produces cyclic ADP-ribose (cADPR).
3D Structures of Cluster of Differentiation 38
Updated on 28-October-2015
