Acetyl-CoA carboxylase

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{{STRUCTURE_2x24| PDB=2x24 | SIZE=400| SCENE= |right|CAPTION=Bovine acetyl-CoA carboxylase CT domain dimer complex with inhibitor, [[2x24]] }}
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<StructureSection load='1bdo' size='450' side='right' scene='' caption=''>
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== Function ==
== Function ==
'''Acetyl-CoA carboxylase''' (ACC) catalyzes the irreversible carboxylation of acetyl-CoA to malonyl-CoA. Malonyl-CoA is a building block in in the biosynthesis of fatty acids. ACC is biotin- and ATP-dependent enzyme. In mammals, 2 forms of ACC exist. ACC1 and ACC2 differ in their tissue distribution and function.
'''Acetyl-CoA carboxylase''' (ACC) catalyzes the irreversible carboxylation of acetyl-CoA to malonyl-CoA. Malonyl-CoA is a building block in in the biosynthesis of fatty acids. ACC is biotin- and ATP-dependent enzyme. In mammals, 2 forms of ACC exist. ACC1 and ACC2 differ in their tissue distribution and function.

Revision as of 08:43, 2 November 2015

PDB ID 1bdo

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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