Annexin

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{{STRUCTURE_1ain| PDB=1ain | SIZE=400| SCENE=Annexin/Cv/2 |right|CAPTION=Human annexin I complex with Ca+2 ions, [[1ain]] }}
{{STRUCTURE_1ain| PDB=1ain | SIZE=400| SCENE=Annexin/Cv/2 |right|CAPTION=Human annexin I complex with Ca+2 ions, [[1ain]] }}
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[[Annexin|Annexins]] are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. They consist of 2 domains - the C-terminal core and the N-terminal head. Annexins divide into species and are numbered from I to XII. '''Annexin V''' is the most abundant scaffolding protein. '''Annexin E1''' (AnE1) is associated with tubulin in trophozoites of ''Giardia lamblia'' and forms local slubs in the flagella. In the annexin image calcium ions are shown as green balls.
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== Function ==
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[[Annexin|Annexins]] are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. Annexins divide into species and are numbered from I to XII. '''Annexin V''' is the most abundant scaffolding protein. '''Annexin E1''' (AnE1) is associated with tubulin in trophozoites of ''Giardia lamblia'' and forms local slubs in the flagella. In the annexin image calcium ions are shown as green balls.
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== Structural highlights ==
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Annexins consist of 2 domains - the C-terminal core and the N-terminal head.
==3D structures of annexin==
==3D structures of annexin==

Revision as of 09:02, 2 November 2015

Template:STRUCTURE 1ain

Function

Annexins are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. Annexins divide into species and are numbered from I to XII. Annexin V is the most abundant scaffolding protein. Annexin E1 (AnE1) is associated with tubulin in trophozoites of Giardia lamblia and forms local slubs in the flagella. In the annexin image calcium ions are shown as green balls.

Structural highlights

Annexins consist of 2 domains - the C-terminal core and the N-terminal head.

3D structures of annexin

Updated on 02-November-2015

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Michal Harel, Alexander Berchansky, Jaime Prilusky

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