Anthrax protective antigen
From Proteopedia
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<StructureSection load='1acc' size='340' side='right' caption='Anthrax protective antigen (PA83) complex with Ca+2 ions (PDB code [[1acc]])' scene=''> | <StructureSection load='1acc' size='340' side='right' caption='Anthrax protective antigen (PA83) complex with Ca+2 ions (PDB code [[1acc]])' scene=''> | ||
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* Domain 1 is the N terminal. It contains the furin protease cleavage site enabling the release of PA20.<br /> | * Domain 1 is the N terminal. It contains the furin protease cleavage site enabling the release of PA20.<br /> | ||
* Domain 2 is the heptamerization domain of PA63.<br /> | * Domain 2 is the heptamerization domain of PA63.<br /> | ||
| - | * Domain 3 forms the heptameric pore with domain 2 and enabling LF and | + | * Domain 3 forms the heptameric pore with domain 2 and enabling LF and EF to penetrate the cell.<br /> |
* Domain 4 is important for receptor recognition and pore formation. <br /> | * Domain 4 is important for receptor recognition and pore formation. <br /> | ||
Revision as of 10:25, 2 November 2015
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