Arylamine N-acetyltransferase
From Proteopedia
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| - | '''Arylamine N-acetyltransferase''' (NAT) catalyzes the transfer of an acetyl group from acetyl-CoA to an arylamine. Acetylation is a major route of biotransformation for many arylamines and hydrazine drugs and known carcinogens like cigarette smoke. The levels of NAT in the body has important consequences with regard to an individual’s susceptibility to certain drug-induced toxicities and cancer. | + | |
| + | == Function == | ||
| + | |||
| + | '''Arylamine N-acetyltransferase''' (NAT) catalyzes the transfer of an acetyl group from acetyl-CoA to an arylamine. | ||
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| + | == Relevance == | ||
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| + | Acetylation is a major route of biotransformation for many arylamines and hydrazine drugs and known carcinogens like cigarette smoke. The levels of NAT in the body has important consequences with regard to an individual’s susceptibility to certain drug-induced toxicities and cancer. | ||
==3D structures of arylamine N-acetyltransferase== | ==3D structures of arylamine N-acetyltransferase== | ||
Revision as of 11:53, 4 November 2015
Function
Arylamine N-acetyltransferase (NAT) catalyzes the transfer of an acetyl group from acetyl-CoA to an arylamine.
Relevance
Acetylation is a major route of biotransformation for many arylamines and hydrazine drugs and known carcinogens like cigarette smoke. The levels of NAT in the body has important consequences with regard to an individual’s susceptibility to certain drug-induced toxicities and cancer.
3D structures of arylamine N-acetyltransferase
Updated on 04-November-2015
