Beta-2 microglobulin
From Proteopedia
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[[Beta-2 microglobulin]] ('''B2M''') is a component of MHC class I system. B2M associates with MHC class I α chain, CD1 and Qa. Loss of B2M function causes iron excess. For more details, see: [[Human beta two microglobulin]]. | [[Beta-2 microglobulin]] ('''B2M''') is a component of MHC class I system. B2M associates with MHC class I α chain, CD1 and Qa. Loss of B2M function causes iron excess. For more details, see: [[Human beta two microglobulin]]. | ||
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| + | == Disease == | ||
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| + | Elevated B2M levels are found in patients of live cirhossis. | ||
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| + | == Relevance == | ||
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| + | B2M is used as a marker for certain types of blood cell cancer. It can indicate the spread and severity of myeloma. | ||
== 3D Structures of β-2 microglobulin == | == 3D Structures of β-2 microglobulin == | ||
Revision as of 09:29, 10 November 2015
Beta-2 microglobulin (B2M) is a component of MHC class I system. B2M associates with MHC class I α chain, CD1 and Qa. Loss of B2M function causes iron excess. For more details, see: Human beta two microglobulin.
Disease
Elevated B2M levels are found in patients of live cirhossis.
Relevance
B2M is used as a marker for certain types of blood cell cancer. It can indicate the spread and severity of myeloma.
3D Structures of β-2 microglobulin
Updated on 10-November-2015
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Joel L. Sussman, Alexander Berchansky, David Canner
